历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Arctigenin, a natural ERβ ligand occurring in edible burdock, accelerates focal adhesion disassembly of colon epithelial cells via enhancing autophagic degradation of paxillin to facilitate mucosal healing in ulcerative colitis
                        

产品名称：ERβ-KO

研究领域：溃疡性结肠炎; 肠道粘膜修复

发表年份：2026 发表杂志：Food & Function

                            
                            Chemotherapy triggers immune evasion by fostering LEPR+ Kupffer cell differentiation in liver metastases
                        

产品名称：Clec4f-2A-CreERT2; Mertk-Flox; M-NSG

研究领域：肝癌; 肿瘤转移; 免疫逃逸

发表年份：2026 发表杂志：CANCER CELL

                            
                            Lipid oxidation reprogramming in cancer-associated fibroblasts enhances CD8+ T cell cytotoxicity and therapeutic response
                        

产品名称：Pdgfra-Cre

研究领域：脂质氧化; 肿瘤微环境; 癌症免疫治疗; 代谢重编程

发表年份：2026 发表杂志：CANCER CELL

                            
                            THY1+ cancer stem cells drive metastasis through a pseudohypoxic state shaped by neutrophil-derived mitochondria
                        

产品名称：H22

研究领域：肿瘤干细胞; 转移; 肿瘤微环境; 中性粒细胞

发表年份：2026 发表杂志：NATURE CELL BIOLOGY

Genetic recording of pancreatic beta cell proliferation

产品名称：饲养繁育

研究领域：糖尿病; 胰岛β细胞再生; 谱系追踪

发表年份：2026 发表杂志：PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

                            
                            Hepatocyte PLAGL2 deficiency alleviates MASH through MYD88-licensed inactivation of inflammasome
                        

产品名称：Plagl2-Flox; Alb-Cre

研究领域：MASH; 炎症小体

发表年份：2026 发表杂志：Cell Reports

                            
                            A bone-derived hormone permits rapid visual escape via GPR37 receptor in a subpopulation of VTA GABAergic neurons
                        

产品名称：OCN-KO; Gpr158-KO; GPR37-Flox

研究领域：神经科学; 骨钙素; 行为学

发表年份：2026 发表杂志：NEURON

                            
                            PD-L1-Binding Antigen Presenters: Redirecting Vaccine-Induced Antibodies for Cancer Immunotherapy
                        

产品名称：M-NSG

研究领域：癌症免疫治疗; 疫苗设计

发表年份：2026 发表杂志：Advanced Science

                            
                            USP20, a Super-enhancer Regulated Gene, Promotes Acute Myeloid Leukemia Progression through CTNNB1 Deubiquitination
                        

产品名称：M-NSG

研究领域：白血病; 表观遗传学; 泛素化修饰

发表年份：2026 发表杂志：International Journal of Biological Sciences

                            
                            Thrombospondin-1-mediated macrophage efferocytosis dysfunction exacerbates intestinal pathology in Hirschsprung's disease
                        

产品名称：Thbs1-KO

研究领域：先天性巨结肠; 巨噬细胞功能

发表年份：2026 发表杂志：INTERNATIONAL IMMUNOPHARMACOLOGY

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Arctigenin, a natural ERβ ligand occurring in edible burdock, accelerates focal adhesion disassembly of colon epithelial cells via enhancing autophagic degradation of paxillin to facilitate mucosal healing in ulcerative colitis

Chemotherapy triggers immune evasion by fostering LEPR+ Kupffer cell differentiation in liver metastases

Lipid oxidation reprogramming in cancer-associated fibroblasts enhances CD8+ T cell cytotoxicity and therapeutic response

THY1+ cancer stem cells drive metastasis through a pseudohypoxic state shaped by neutrophil-derived mitochondria

Genetic recording of pancreatic beta cell proliferation

Hepatocyte PLAGL2 deficiency alleviates MASH through MYD88-licensed inactivation of inflammasome

A bone-derived hormone permits rapid visual escape via GPR37 receptor in a subpopulation of VTA GABAergic neurons

PD-L1-Binding Antigen Presenters: Redirecting Vaccine-Induced Antibodies for Cancer Immunotherapy

USP20, a Super-enhancer Regulated Gene, Promotes Acute Myeloid Leukemia Progression through CTNNB1 Deubiquitination

Thrombospondin-1-mediated macrophage efferocytosis dysfunction exacerbates intestinal pathology in Hirschsprung's disease

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