历年文献基因敲除小鼠_转基因小鼠定制

                            
                            TREM2 Facilitates Myelin Debris Clearance but Exacerbates Chronic Inflammation and Fibrosis After Spinal Cord Injury
                        

产品名称：Trem2-KO

研究领域：脊髓损伤

发表年份：2026 发表杂志：CNS Neuroscience & Therapeutics

                            
                            Minnelide ameliorates Col4a5+/− mice by upregulating Col4a5 and alleviating endoplasmic reticulum stress
                        

产品名称：Col4a5-R471X

研究领域：Alport综合征

发表年份：2026 发表杂志：Frontiers in Pharmacology

                            
                            Estrogen regulates cognitive function in APP/PS1 female mice via modulation of IDO1-mediated Trp/Kyn metabolism through ERβ
                        

产品名称：APP/PS1

研究领域：阿尔茨海默病

发表年份：2026 发表杂志：HORMONES AND BEHAVIOR

                            
                            CEACAM6 silencing suppresses tumour growth and sensitises cholangiocarcinoma to cisplatin
                        

产品名称：BALB/c Nude

研究领域：胆管癌; 肿瘤治疗; 化疗增敏

发表年份：2026 发表杂志：Clinical and Translational Discovery

                            
                            RNF26 regulating tumor immunogenicity of hepatocellular carcinoma by degrading GRP78 and instigating ER stress
                        

产品名称：HBC-tg

研究领域：肝细胞癌; 免疫抑制

发表年份：2026 发表杂志：DRUG RESISTANCE UPDATES

                            
                            Biomimetic SIRPα–CAR Engineering for In Situ Macrophage Reprogramming and Potent Solid Tumor Immunotherapy
                        

产品名称：MC38–hCD47

研究领域：细胞免疫疗法; 基于SIRPα的嵌合抗原受体

发表年份：2026 发表杂志：ADVANCED FUNCTIONAL MATERIALS

                            
                            ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC-I Antigen Presentation That Promotes Tumor Immune Evasion
                        

产品名称：M-NSG

研究领域：肿瘤细胞焦亡和抗原呈递

发表年份：2026 发表杂志：Advanced Science

                            
                            A novel human acute myeloid leukemia cell line SDEY-AML1 with KMT2A: MLLT3, IKZF1: EVX1 fusions exhibits high tumorigenicity in NSG mice
                        

产品名称：M-NSG

研究领域：急性髓系白血病

发表年份：2026 发表杂志：Scientific Reports

                            
                            Interleukin-10 expressing B lineage cells in visceral adipose tissue protect against aging-related insulin resistance and extend lifespan
                        

产品名称：IL10-Flox

研究领域：内脏脂肪组织炎症

发表年份：2026 发表杂志：Nature Communications

                            
                            MD2 suppresses anaplastic thyroid Cancer progression by reprogramming macrophages via USP15-mediated FHL1 Deubiquitination
                        

产品名称：BALB/c Nude

研究领域：肿瘤相关巨噬细胞; TAM重编程

发表年份：2026 发表杂志：INTERNATIONAL IMMUNOPHARMACOLOGY

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TREM2 Facilitates Myelin Debris Clearance but Exacerbates Chronic Inflammation and Fibrosis After Spinal Cord Injury

Minnelide ameliorates Col4a5+/− mice by upregulating Col4a5 and alleviating endoplasmic reticulum stress

Estrogen regulates cognitive function in APP/PS1 female mice via modulation of IDO1-mediated Trp/Kyn metabolism through ERβ

CEACAM6 silencing suppresses tumour growth and sensitises cholangiocarcinoma to cisplatin

RNF26 regulating tumor immunogenicity of hepatocellular carcinoma by degrading GRP78 and instigating ER stress

Biomimetic SIRPα–CAR Engineering for In Situ Macrophage Reprogramming and Potent Solid Tumor Immunotherapy

ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC-I Antigen Presentation That Promotes Tumor Immune Evasion

A novel human acute myeloid leukemia cell line SDEY-AML1 with KMT2A: MLLT3, IKZF1: EVX1 fusions exhibits high tumorigenicity in NSG mice

Interleukin-10 expressing B lineage cells in visceral adipose tissue protect against aging-related insulin resistance and extend lifespan

MD2 suppresses anaplastic thyroid Cancer progression by reprogramming macrophages via USP15-mediated FHL1 Deubiquitination

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