历年文献基因敲除小鼠_转基因小鼠定制

                            
                            CYFIP2 deficiency ameliorates renal interstitial fibrosis through attenuating tubular senescence in hypertensive nephropathy
                        

产品名称：Cyfip2-Flox

研究领域：肾间质纤维化;高血压

发表年份：2026 发表杂志：ACTA PHARMACOLOGICA SINICA

                            
                            Rapidly Evolved PD-1 for an Enhance Receptor and Checkpoint Inhibitor in Immunotherapy
                        

产品名称：hPD-L1

研究领域：肿瘤免疫;免疫检查点

发表年份：2026 发表杂志：Molecular Therapy Oncology

                            
                            Neuronal deletion of PDE7A averts morphine-induced behavioral plasticity and impairs downstream AKT signaling
                        

产品名称：Pde7a-Flox

研究领域：神经

发表年份：2026 发表杂志：MOLECULAR BIOLOGY REPORTS

                            
                            ADAMTS4 elicits myeloid-derived immune cell recruitment and liver fibrogenesis in metabolic dysfunction-associated steatotic liver disease
                        

产品名称：Adamts4-Flox

研究领域：肝纤维化;代谢

发表年份：2026 发表杂志：Signal Transduction and Targeted Therapy

                            
                            CD248 acts as a mechanosensory switch in fibroblast subsets to establish distinct pathological niches in renal fibrosis
                        

产品名称：Cd248-CreERT2;Rosa26-LSL-tdTomato-DTR;Co1la2-CreERT2;Cd248-Flox

研究领域：肾纤维化

发表年份：2026 发表杂志：Nature Communications

                            
                            Single-cell Stereo-seq reveals regulatory mechanisms driving regeneration of injured proximal tubules during AKI
                        

产品名称：SD

研究领域：急性肾损伤

发表年份：2026 发表杂志：Nature Communications

                            
                            Enhancing CAR-T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF-Mediated Angiogenesis
                        

产品名称：Cd4-CreERT2

研究领域：肿瘤;Car-T疗法

发表年份：2026 发表杂志：Advanced Science

                            
                            GPR75 Genetic Manipulations in Mice Reveal Central Mechanism for Weight Loss Independent of Developmental Effects
                        

产品名称：Gpr75-Flox;R26-CreERT2

研究领域：代谢;减重;发育

发表年份：2026 发表杂志：Molecular Metabolism

                            
                            ROCK Inhibition Reprograms Microglial Polarization to Promote Neuroprotection via NOX2/ROS/TXNIP Suppression
                        

产品名称：ROCK2-KO

研究领域：神经

发表年份：2026 发表杂志：ANTIOXIDANTS & REDOX SIGNALING

                            
                            ACTR3 enhances the hyperproliferation of psoriatic keratinocytes by activating the TAK1-MK2-HSP27 pathway
                        

产品名称：ACTR3-K42A

研究领域：银屑病

发表年份：2026 发表杂志：FEBS Journal

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CYFIP2 deficiency ameliorates renal interstitial fibrosis through attenuating tubular senescence in hypertensive nephropathy

Rapidly Evolved PD-1 for an Enhance Receptor and Checkpoint Inhibitor in Immunotherapy

Neuronal deletion of PDE7A averts morphine-induced behavioral plasticity and impairs downstream AKT signaling

ADAMTS4 elicits myeloid-derived immune cell recruitment and liver fibrogenesis in metabolic dysfunction-associated steatotic liver disease

CD248 acts as a mechanosensory switch in fibroblast subsets to establish distinct pathological niches in renal fibrosis

Single-cell Stereo-seq reveals regulatory mechanisms driving regeneration of injured proximal tubules during AKI

Enhancing CAR-T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF-Mediated Angiogenesis

GPR75 Genetic Manipulations in Mice Reveal Central Mechanism for Weight Loss Independent of Developmental Effects

ROCK Inhibition Reprograms Microglial Polarization to Promote Neuroprotection via NOX2/ROS/TXNIP Suppression

ACTR3 enhances the hyperproliferation of psoriatic keratinocytes by activating the TAK1-MK2-HSP27 pathway

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