历年文献基因敲除小鼠_转基因小鼠定制

The role of astrocytic GSDME in Sepsis-associated cognitive dysfunction

产品名称：Gsdme-KO

研究领域：败血症相关脑病; 神经功能障碍

发表年份：2026 发表杂志：INTERNATIONAL IMMUNOPHARMACOLOGY

                            
                            Targeting the Vim–PGI2 Pathway Enhances CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer
                        

产品名称：C57BL/6

研究领域：乳腺癌; 肿瘤免疫

发表年份：2026 发表杂志：HUMAN MUTATION

                            
                            Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy
                        

产品名称：SPARTIN-Flox

研究领域：老年骨质疏松症; 骨生成

发表年份：2026 发表杂志：Advanced Science

                            
                            T Cell-Independent Role of PD-L1 in Kidney Repair: Mitigation of Tubular DNA Damage via PD-L1/BRCA1 Interaction Following AKI
                        

产品名称：PD-L1-Flox

研究领域：急性肾损伤; DNA损伤

发表年份：2026 发表杂志：Advanced Science

                            
                            Intracellular LRG1 recruits MARCH2 to ubiquitinate and degrade endothelial VE-cadherin in septic lung injury
                        

产品名称：Lrg1-KO

研究领域：败血症急性肺损伤; VE-钙粘蛋白

发表年份：2026 发表杂志：ACTA PHARMACOLOGICA SINICA

                            
                            Keratin 20 deficiency phenocopies human UAB and drives bladder fibrosis via a mechanotransduction-TGF-β axis
                        

产品名称：Krt20-Cre-tdTomato

研究领域：纤维化; 下尿路症状

发表年份：2026 发表杂志：iScience

                            
                            Endothelial USP2a-METTL16 loop potentiates IL-6 signaling via m6A-mediated IL-6R stabilization in pulmonary vascular remodeling
                        

产品名称：SD

研究领域：肺动脉高压

发表年份：2026 发表杂志：CELL DEATH AND DIFFERENTIATION

                            
                            XIAP Deficiency Impairs Colonic Tuft Cell Development and Predisposes to Crohn's Disease
                        

产品名称：Xiap-KO; Ascl2-Flox

研究领域：克罗恩病; 结肠簇细胞发育

发表年份：2026 发表杂志：MedComm

                            
                            miR-495-3p promotes chronic obstructive pulmonary disease by activating ferroptosis in lung epithelial cells through regulation of the ETS1/GPX4 axis
                        

产品名称：C57BL/6

研究领域：慢性阻塞性肺病; 铁死亡

发表年份：2026 发表杂志：MOLECULAR BIOLOGY REPORTS

                            
                            A Nano-Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast-Immune Communication via CCL2 Sequestration
                        

产品名称：Ccl2-Flox;Postn-2A-CreERT2

研究领域：慢性心力衰竭; 成纤维细胞-免疫通讯

发表年份：2026 发表杂志：ADVANCED MATERIALS

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The role of astrocytic GSDME in Sepsis-associated cognitive dysfunction

Targeting the Vim–PGI2 Pathway Enhances CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

T Cell-Independent Role of PD-L1 in Kidney Repair: Mitigation of Tubular DNA Damage via PD-L1/BRCA1 Interaction Following AKI

Intracellular LRG1 recruits MARCH2 to ubiquitinate and degrade endothelial VE-cadherin in septic lung injury

Keratin 20 deficiency phenocopies human UAB and drives bladder fibrosis via a mechanotransduction-TGF-β axis

Endothelial USP2a-METTL16 loop potentiates IL-6 signaling via m6A-mediated IL-6R stabilization in pulmonary vascular remodeling

XIAP Deficiency Impairs Colonic Tuft Cell Development and Predisposes to Crohn's Disease

miR-495-3p promotes chronic obstructive pulmonary disease by activating ferroptosis in lung epithelial cells through regulation of the ETS1/GPX4 axis

A Nano-Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast-Immune Communication via CCL2 Sequestration

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