历年文献基因敲除小鼠_转基因小鼠定制

RBFOX2 suppresses NETosis and glioma growth via 5hmC-dependent PDGFB decay

产品名称：PAD4-KO

研究领域：胶质瘤;mRNA降解;表观转录组

发表年份：2026 发表杂志：Cell Reports

                            
                            Metrnl ameliorates ulcerative colitis by inhibiting NLRP3 inflammasome activation via ASC
                        

产品名称：Metrnl-KO

研究领域：溃疡性结肠炎;NLRP3炎症小体;肠道炎症

发表年份：2026 发表杂志：Scientific Reports

                            
                            Cell-type-specific CB1R signaling modulates prefrontal synaptic responses to HF-rTMS in chronically stressed mice
                        

产品名称：Cnr1-Flox

研究领域：慢性应激;高频重复经颅磁刺激;前额叶皮层;突触可塑性

发表年份：2026 发表杂志：BEHAVIOURAL BRAIN RESEARCH

Iron-mediated ferroptosis impairs CAR-T cell function and antitumor efficacy

产品名称：M-NSG

研究领域：铁死亡;CAR-T;抗肿瘤疗效

发表年份：2026 发表杂志：Nature Cancer

                            
                            The disulfonic acid ANDS disrupts ANP32B-p53 interaction to suppress chronic myeloid leukemia
                        

产品名称：Anp32b-Flox

研究领域：慢性骨髓性白血病

发表年份：2026 发表杂志：Nature Communications

                            
                            In Vivo Evidence of Human Organic Anion Transporting Polypeptide (OATP) 1B1 and OATP1B3 Mediated Disposition of Glycyrrhizin and Its Drug–Drug Interactions in Humanized Mice
                        

产品名称：hOATP1B1;hOATP1B3

研究领域：肝脏摄取;药代动力学

发表年份：2026 发表杂志：PHYTOTHERAPY RESEARCH

                            
                            Transient receptor potential vanilloid 4 exacerbates sepsis-induced acute lung injury by promoting endothelial pyroptosis via the Ca2+/Nrf2/GSDMD signaling pathway
                        

产品名称：Trpv4-KO;Nrf2-KO

研究领域：败血症引起的急性肺损伤

发表年份：2026 发表杂志：INTERNATIONAL IMMUNOPHARMACOLOGY

                            
                            Bepirovirsen induces innate immune activation in the liver potentially through TLR8 signaling
                        

产品名称：hTLR8

研究领域：先天免疫激活;肝脏巨噬细胞

发表年份：2026 发表杂志：JHEP Reports

                            
                            Pathogenic signatures and therapeutic evaluation of emergent MPXV Clade Ib in low-susceptibility and immunocompromised mouse models
                        

产品名称：Ifngr1/Ifnar1-KO

研究领域：猴痘

发表年份：2026 发表杂志：BMC MICROBIOLOGY

                            
                            Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interaction
                        

产品名称：Nrf2-KO

研究领域：乙醇诱导的胃黏膜氧化损伤

发表年份：2026 发表杂志：eLife

成品模型资源库

模型定制服务

配套服务

肿瘤药效平台

代谢心血管疾病评价平台

炎症/自身免疫疾病评价平台

神经疾病评价平台

细胞系服务平台

体外药效检测平台

毒理/病理学服务平台

南模动态

资料下载

客户支持

公司简介

公司资质

发展历程

投资者关系活动

投资者教育

发表年份

产品或服务类型

RBFOX2 suppresses NETosis and glioma growth via 5hmC-dependent PDGFB decay

Metrnl ameliorates ulcerative colitis by inhibiting NLRP3 inflammasome activation via ASC

Cell-type-specific CB1R signaling modulates prefrontal synaptic responses to HF-rTMS in chronically stressed mice

Iron-mediated ferroptosis impairs CAR-T cell function and antitumor efficacy

The disulfonic acid ANDS disrupts ANP32B-p53 interaction to suppress chronic myeloid leukemia

In Vivo Evidence of Human Organic Anion Transporting Polypeptide (OATP) 1B1 and OATP1B3 Mediated Disposition of Glycyrrhizin and Its Drug–Drug Interactions in Humanized Mice

Transient receptor potential vanilloid 4 exacerbates sepsis-induced acute lung injury by promoting endothelial pyroptosis via the Ca2+/Nrf2/GSDMD signaling pathway

Bepirovirsen induces innate immune activation in the liver potentially through TLR8 signaling

Pathogenic signatures and therapeutic evaluation of emergent MPXV Clade Ib in low-susceptibility and immunocompromised mouse models

Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interaction

动物健康

健康报告

动物福利

隐私权声明

销售条款与条件

公司资质

发展历程

新闻动态

联系我们