历年文献基因敲除小鼠_转基因小鼠定制

                            
                            NOTCH3 attenuates cytotoxicity via RBPJ-dependent PVR upregulation to influence immunotherapy outcomes in colorectal cancer
                        

产品名称：C57BL/6

研究领域：肿瘤; 结直肠癌

发表年份：2026 发表杂志：Frontiers in Immunology

                            
                            Lactobacillus plantarum AR113 alleviates Western Diet-Induced colitis and liver injury via bidirectional modulation of the Intestinal-Hepatic FXR signaling axis
                        

产品名称：FXR-KO

研究领域：炎症性肠病; 肠道菌群

发表年份：2026 发表杂志：Journal of Advanced Research

                            
                            Netrin-1 disrupt high-fat-diet-induced adipogenesis via the PPARγ and Wnt/β-catenin signaling pathways
                        

产品名称：Ntn1-Flox

研究领域：2型糖尿病; Wnt/β-catenin信号通路

发表年份：2026 发表杂志：Communications Biology

                            
                            Hyperactivation of sympathetic nerves fuels basophil infiltration in atopic dermatitis
                        

产品名称：Id2-Flox

研究领域：交感神经; 特应性皮炎

发表年份：2026 发表杂志：IMMUNITY

                            
                            Structure–Activity-Driven Multicompartment Lipid Nanoparticles for Synergistic mRNA and siRNA Codelivery in Acute Myeloid Leukemia
                        

产品名称：M-NSG

研究领域：急性髓系白血病

发表年份：2026 发表杂志：Journal of the American Chemical Society

                            
                            12R-HETE acts as an endogenous ligand for Nur77 in the intestines and regulates NKp46+ ILC3 development
                        

产品名称：Rag1-KO

研究领域：肠道免疫

发表年份：2026 发表杂志：Science Advances

ADCY7 dictates N-cadherin stability to inhibit HCC metastasis

产品名称：BALB/c nude

研究领域：肿瘤; 肝细胞癌

发表年份：2026 发表杂志：JHEP Reports

                            
                            Crotonylation of STXBP1 exacerbates seizure susceptibility by impairing GABAergic synaptic transmission
                        

产品名称：Stxbp1-K98Q

研究领域：颞叶癫痫; 蛋白质翻译后修饰

发表年份：2026 发表杂志：CELL DEATH AND DIFFERENTIATION

                            
                            3D-cultured hUC-MSC-derived exosomes as macrophage mediators to suppress cholestatic fibrosis in mice via miR-1291–mediated multi-targeted pathways
                        

产品名称：C57BL/6

研究领域：外泌体; 胆汁性肝病

发表年份：2026 发表杂志：CHEMICAL ENGINEERING JOURNAL

                            
                            Integrative Single-Cell and Spatial Transcriptomic Reveals S100A16+ Tumor Endothelial Cells Drive Angiogenesis and Immunosuppression in Hepatocellular Carcinoma
                        

产品名称：S100A16-Flox

研究领域：肿瘤; 肝细胞癌

发表年份：2026 发表杂志：CANCER LETTERS

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NOTCH3 attenuates cytotoxicity via RBPJ-dependent PVR upregulation to influence immunotherapy outcomes in colorectal cancer

Lactobacillus plantarum AR113 alleviates Western Diet-Induced colitis and liver injury via bidirectional modulation of the Intestinal-Hepatic FXR signaling axis

Netrin-1 disrupt high-fat-diet-induced adipogenesis via the PPARγ and Wnt/β-catenin signaling pathways

Hyperactivation of sympathetic nerves fuels basophil infiltration in atopic dermatitis

Structure–Activity-Driven Multicompartment Lipid Nanoparticles for Synergistic mRNA and siRNA Codelivery in Acute Myeloid Leukemia

12R-HETE acts as an endogenous ligand for Nur77 in the intestines and regulates NKp46+ ILC3 development

ADCY7 dictates N-cadherin stability to inhibit HCC metastasis

Crotonylation of STXBP1 exacerbates seizure susceptibility by impairing GABAergic synaptic transmission

3D-cultured hUC-MSC-derived exosomes as macrophage mediators to suppress cholestatic fibrosis in mice via miR-1291–mediated multi-targeted pathways

Integrative Single-Cell and Spatial Transcriptomic Reveals S100A16+ Tumor Endothelial Cells Drive Angiogenesis and Immunosuppression in Hepatocellular Carcinoma

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