历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Schisandrin B exhibits anti‑proliferative effects by inducing ferroptosis in pancreatic cancer
                        

产品名称：Kras-G12D;Pdx1-Cre;Tp53-Flox

研究领域：胰腺癌;铁死亡;抗增殖;天然产物;氧化应激

发表年份：2026 发表杂志：ONCOLOGY REPORTS

                            
                            SNX3 exacerbates hepatic fibrosis by amplifying TGF-β1/Smad signaling pathway in hepatocyte-HSC fibrotic loop
                        

产品名称：Snx3-Flox

研究领域：肝纤维化;肝细胞-肝星状细胞串扰;分选连接蛋白;纤维化环路

发表年份：2026 发表杂志：Acta Pharmaceutica Sinica B

                            
                            GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury
                        

产品名称：Gpr124-Flox

研究领域：创伤性脑损伤;血脑屏障;微血管内皮细胞;神经血管单元;内皮功能

发表年份：2026 发表杂志：Advanced Science

                            
                            Pyridinyl ring defines a noncanonical P1-S1 axis that revamps inhibitor design against coronaviral main proteases
                        

产品名称：CAG-hACE2-IRES-Luc-Tg

研究领域：冠状病毒;主蛋白酶;抑制剂设计;吡啶环;药物化学

发表年份：2026 发表杂志：Cell Reports Physical Science

                            
                            Gut microbial histamine and serotonin promote cerebrovascular angiogenesis: Evidence from moyamoya disease
                        

产品名称：C57BL/6

研究领域：烟雾病;肠道微生物;脑血管生成;肠脑轴

发表年份：2026 发表杂志：Genes & Diseases

                            
                            ZFP91 restricts RSV replication by driving K48-linked ubiquitination and proteasomal degradation of M2-1
                        

产品名称：ZFP91-Flox

研究领域：呼吸道合胞病毒;蛋白酶体降解;抗病毒天然免疫

发表年份：2026 发表杂志：CELLULAR AND MOLECULAR LIFE SCIENCES

                            
                            RNF34 restrains endometriosis through SREBP1-dependent metabolic-immune crosstalk
                        

产品名称：R26-CAG-Luc-2A-EGFP

研究领域：子宫内膜异位症;代谢-免疫串扰;脂质代谢;泛素连接酶

发表年份：2026 发表杂志：CELLULAR AND MOLECULAR LIFE SCIENCES

                            
                            Cucurbitacin B attenuates bleomycin-induced pulmonary fibrosis by inhibiting M2 macrophage polarization via PI3K/AKT/mTOR signaling
                        

产品名称：C57BL/6

研究领域：肺纤维化;葫芦素B;M2巨噬细胞极化;博来霉素

发表年份：2026 发表杂志：INTERNATIONAL IMMUNOPHARMACOLOGY

                            
                            H3K18la- driven neutrophil secretory autophagy promotes pulmonary endothelial dysfunction in sepsis-induced lung injury
                        

产品名称：Ep300-Flox;Lyz2-CreERT2

研究领域：脓毒症肺损伤;组蛋白乳酸化;中性粒细胞;分泌性自噬;内皮功能障碍

发表年份：2026 发表杂志：Autophagy

                            
                            VSMC-derived 3HAA activates AhR to drive abdominal aortic aneurysm formation via the p62–Nrf2 axis
                        

产品名称：Kynu-Flox

研究领域：腹主动脉瘤;色氨酸代谢

发表年份：2026 发表杂志：Redox Biology

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Schisandrin B exhibits anti‑proliferative effects by inducing ferroptosis in pancreatic cancer

SNX3 exacerbates hepatic fibrosis by amplifying TGF-β1/Smad signaling pathway in hepatocyte-HSC fibrotic loop

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Pyridinyl ring defines a noncanonical P1-S1 axis that revamps inhibitor design against coronaviral main proteases

Gut microbial histamine and serotonin promote cerebrovascular angiogenesis: Evidence from moyamoya disease

ZFP91 restricts RSV replication by driving K48-linked ubiquitination and proteasomal degradation of M2-1

RNF34 restrains endometriosis through SREBP1-dependent metabolic-immune crosstalk

Cucurbitacin B attenuates bleomycin-induced pulmonary fibrosis by inhibiting M2 macrophage polarization via PI3K/AKT/mTOR signaling

H3K18la- driven neutrophil secretory autophagy promotes pulmonary endothelial dysfunction in sepsis-induced lung injury

VSMC-derived 3HAA activates AhR to drive abdominal aortic aneurysm formation via the p62–Nrf2 axis

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