历年文献基因敲除小鼠_转基因小鼠定制

                            
                            MiR-1a-3p/Fcgr4-dependent osteoclast activation regulates pathological bone loss
                        

产品名称：C57BL/6

研究领域：骨质疏松症; 骨免疫学

发表年份：2026 发表杂志：Frontiers in Immunology

                            
                            Spatial and single-cell transcriptomic profiling reveals interplay between SRGN-associated epithelial programs and C1QC+ macrophages in early LUAD progression
                        

产品名称：A/J

研究领域：巨噬细胞; 肺腺癌

发表年份：2026 发表杂志：Journal of Translational Medicine

                            
                            Hepatic Senp2 Deletion Resolves the Angiogenic Switch in Fibrosis via β-Catenin/LECT2
                        

产品名称：Senp2-Flox

研究领域：血管生成; 肝纤维化

发表年份：2026 发表杂志：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

                            
                            Nociceptive sensory nerves induce an IL4Rαhi anti-inflammatory macrophage subset that protects against kidney ischemia-reperfusion injury
                        

产品名称：R26-CAG-LSL-tdTomato; R26-CAG-LSL-R-tdTomato-2A-DTR ;Trpv1-Cre

研究领域：缺血再灌注损伤; 炎症

发表年份：2026 发表杂志：KIDNEY INTERNATIONAL

                            
                            Bile Acid Retention Impairs Tumoral Antigen Presentation and Intrinsic Tumor Suppression in MASH-HCC
                        

产品名称：Ffar4-Flox

研究领域：肝癌; 肿瘤免疫治疗

发表年份：2026 发表杂志：CANCER LETTERS

                            
                            FLRT2 promotes foam cell formation and atherosclerosis by inhibiting USP22-mediated ABCA1 deubiquitination
                        

产品名称：Apoe-KO; Flrt2-Flox

研究领域：心血管疾病; 动脉粥样硬化

发表年份：2026 发表杂志：ACTA PHARMACOLOGICA SINICA

                            
                            TGF-β inhibition enhances anti-tumor immunity and sensitizes PD-1 blockade therapy of bone marrow-derived myofibroblasts-induced "immunotherapy resistance" tumor model
                        

产品名称：C57BL/6

研究领域：肿瘤; 肿瘤免疫治疗

发表年份：2026 发表杂志：CANCER IMMUNOLOGY IMMUNOTHERAPY

                            
                            The miR-30c-5p/SOCS3 axis is a potential driver of inflammation and metabolic imbalance in Duchenne muscular dystrophy
                        

产品名称：MDX

研究领域：杜氏肌营养不良症; 炎症; 代谢功能障碍

发表年份：2026 发表杂志：Frontiers in Cell and Developmental Biology

                            
                            CTSZ-dependent anoikis resistance enhances malignant characters of glioblastoma via NF-κB signaling
                        

产品名称：BALB/c Nude

研究领域：胶质母细胞瘤; NF-κB信号

发表年份：2026 发表杂志：iScience

                            
                            Hint2 deficiency aggravates mitochondria-associated ferroptosis in lung ischemia-reperfusion injury
                        

产品名称：Hint2-Flox

研究领域：肺缺血-再灌注损伤; 铁死亡

发表年份：2026 发表杂志：iScience

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MiR-1a-3p/Fcgr4-dependent osteoclast activation regulates pathological bone loss

Spatial and single-cell transcriptomic profiling reveals interplay between SRGN-associated epithelial programs and C1QC+ macrophages in early LUAD progression

Hepatic Senp2 Deletion Resolves the Angiogenic Switch in Fibrosis via β-Catenin/LECT2

Nociceptive sensory nerves induce an IL4Rαhi anti-inflammatory macrophage subset that protects against kidney ischemia-reperfusion injury

Bile Acid Retention Impairs Tumoral Antigen Presentation and Intrinsic Tumor Suppression in MASH-HCC

FLRT2 promotes foam cell formation and atherosclerosis by inhibiting USP22-mediated ABCA1 deubiquitination

TGF-β inhibition enhances anti-tumor immunity and sensitizes PD-1 blockade therapy of bone marrow-derived myofibroblasts-induced "immunotherapy resistance" tumor model

The miR-30c-5p/SOCS3 axis is a potential driver of inflammation and metabolic imbalance in Duchenne muscular dystrophy

CTSZ-dependent anoikis resistance enhances malignant characters of glioblastoma via NF-κB signaling

Hint2 deficiency aggravates mitochondria-associated ferroptosis in lung ischemia-reperfusion injury

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