历年文献基因敲除小鼠_转基因小鼠定制

                            
                            ChREBP Is Dispensable for Myofiber Type Switch but Promotes Skeletal Muscle Regeneration
                        

产品名称：MCK-Cre

研究领域：骨骼肌再生; 代谢

发表年份：2026 发表杂志：Nutrients

                            
                            NFAT5 in alveolar macrophages exacerbates seawater-induced acute lung injury via PFKP-driven glycolysis
                        

产品名称：Siglec1-Cre

研究领域：急性肺损伤; 巨噬细胞免疫

发表年份：2026 发表杂志：CELLULAR SIGNALLING

                            
                            Liver endothelial zonation orchestrates hepatic steatosis onset through retinoic acid–regulated FGF1
                        

产品名称：Fgf1-Flox

研究领域：肝脏脂肪变性;肝窦内皮细胞分区;视黄酸;非酒精性脂肪性肝病

发表年份：2026 发表杂志：Science Advances

                            
                            PCSK9 promotes aging-related cardiac calcification by inducing osteogenic differentiation of cardiac fibroblasts
                        

产品名称：PCSK9-KO

研究领域：心血管; 衰老

发表年份：2026 发表杂志：MECHANISMS OF AGEING AND DEVELOPMENT

                            
                            SMN haploinsufficiency exacerbates high glucose dialysate-induced peritoneal inflammation and fibrosis via mTOR/NFκB signaling pathway
                        

产品名称：SMN-KO

研究领域：腹膜纤维化; 炎症

发表年份：2026 发表杂志：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

                            
                            DCAF7 enhances atherosclerosis in vascular endothelial cells by promoting SLC40A1 transcription through facilitating TNF-mediated NF-κB function
                        

产品名称：DCAF7-KO; ApoE-KO

研究领域：动脉粥样硬化; 心血管

发表年份：2026 发表杂志：Biochemistry and Biophysics Reports

                            
                            Macrophage-mediated brain-bone marrow crosstalk promotes chronic stress-induced glioma growth
                        

产品名称：Trp53-Flox;Nf1-Flox

研究领域：慢性应激;胶质瘤;脑-骨髓轴;巨噬细胞;肿瘤微环境;神经免疫

发表年份：2026 发表杂志：CANCER CELL

                            
                            Trans-presentation of IL-6Rα by macrophages drives colorectal cancer development
                        

产品名称：Vil-Cre

研究领域：结直肠癌;巨噬细胞;IL-6信号;肿瘤炎症;免疫微环境

发表年份：2026 发表杂志：Cell Reports

                            
                            Wnt/Chemerin Signaling Involved in Exercise Training Preventing Diaphragm Dysfunction Induced by Cigarette Smoke
                        

产品名称：Cmklr1-KO

研究领域：膈肌功能障碍;运动训练

发表年份：2026 发表杂志：Biomedicines

Tmem67 Is Required for Spermiogenesis and Male Fertility in Mice

产品名称：Stra8-Cre;Amh-Cre

研究领域：精子形成;雄性生育力;纤毛相关蛋白;基因必需性

发表年份：2026 发表杂志：FASEB JOURNAL

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ChREBP Is Dispensable for Myofiber Type Switch but Promotes Skeletal Muscle Regeneration

NFAT5 in alveolar macrophages exacerbates seawater-induced acute lung injury via PFKP-driven glycolysis

Liver endothelial zonation orchestrates hepatic steatosis onset through retinoic acid–regulated FGF1

PCSK9 promotes aging-related cardiac calcification by inducing osteogenic differentiation of cardiac fibroblasts

SMN haploinsufficiency exacerbates high glucose dialysate-induced peritoneal inflammation and fibrosis via mTOR/NFκB signaling pathway

DCAF7 enhances atherosclerosis in vascular endothelial cells by promoting SLC40A1 transcription through facilitating TNF-mediated NF-κB function

Macrophage-mediated brain-bone marrow crosstalk promotes chronic stress-induced glioma growth

Trans-presentation of IL-6Rα by macrophages drives colorectal cancer development

Wnt/Chemerin Signaling Involved in Exercise Training Preventing Diaphragm Dysfunction Induced by Cigarette Smoke

Tmem67 Is Required for Spermiogenesis and Male Fertility in Mice

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