历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Preclinical Evaluation of AHT-102, a CLDN18.2 × CD3 Bispecific Antibody: Pharmacokinetics, Anti-Tumor Efficacy, Tissue Distribution, and Safety Profile
                        

产品名称：M-NSG

研究领域：抗肿瘤; 双特异性抗体

发表年份：2026 发表杂志：DRUGS IN R&D

                            
                            Law-NQO1 redox boosts the pentose phosphate pathway to confer stem-like properties and antitumor durability in effector CD8+ T cells
                        

产品名称：C57BL/6

研究领域：代谢重编程; 抗肿瘤

发表年份：2026 发表杂志：Cell Chemical Biology

                            
                            A thermosensitive hydrogel encapsulating 2-DG alleviates periodontitis by inhibiting glycolysis and effector response of Th17 cells
                        

产品名称：Il17A-KO

研究领域：牙周炎; 糖酵解

发表年份：2026 发表杂志：Frontiers in Pharmacology

                            
                            Pleiotrophin promotes megakaryocyte differentiation and thrombocytopoiesis by regulating PTPRZ1-Fyn-Akt signaling in thrombocytopenia after allo-HSCT
                        

产品名称：PTPRZ1-KO

研究领域：血小板减少症

发表年份：2026 发表杂志：THROMBOSIS AND HAEMOSTASIS

                            
                            Cross-Species scRNA-seq Finds Ideal Mouse Models for Aortic Dissection Mechanisms
                        

产品名称：Apoe-KO

研究领域：主动脉夹层

发表年份：2026 发表杂志：iScience

                            
                            Intratumoral bacterium Enterocloster bolteae promotes hepatocellular carcinoma progression by directly binding tumor cells
                        

产品名称：HBV-Tg

研究领域：肠道菌群; 肝细胞癌

发表年份：2026 发表杂志：Cell Host & Microbe

                            
                            Ribonuclease 5/Angiogenin Suppresses Intestinal Tumor Initiation by Maintaining Crypt Homeostasis
                        

产品名称：Apc-L850X

研究领域：肠道肿瘤

发表年份：2026 发表杂志：CANCER RESEARCH

                            
                            Fibroblast‐Derived Microfibrillar‐Associated Protein 5 Exerts Cardioprotective Effects After Myocardial Infarction by Activating the NOTCH2 Signaling in Cardiomyocytes
                        

产品名称：Mfap5-KO

研究领域：心肌梗死

发表年份：2026 发表杂志：Journal of the American Heart Association

                            
                            Commensal enteric virome regulates intestinal carbohydrate digestion and absorption
                        

产品名称：Cd74-KO

研究领域：肠道病毒; 代谢调节

发表年份：2026 发表杂志：Cell Host & Microbe

                            
                            WWP2 underlies ROS-induced granulosa cell apoptosis by promoting ubiquitination of BAK in polycystic ovary syndrome
                        

产品名称：Wwp2-KO

研究领域：多囊卵巢综合征; 颗粒瘤细胞

发表年份：2026 发表杂志：Cell Death & Disease

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Preclinical Evaluation of AHT-102, a CLDN18.2 × CD3 Bispecific Antibody: Pharmacokinetics, Anti-Tumor Efficacy, Tissue Distribution, and Safety Profile

Law-NQO1 redox boosts the pentose phosphate pathway to confer stem-like properties and antitumor durability in effector CD8+ T cells

A thermosensitive hydrogel encapsulating 2-DG alleviates periodontitis by inhibiting glycolysis and effector response of Th17 cells

Pleiotrophin promotes megakaryocyte differentiation and thrombocytopoiesis by regulating PTPRZ1-Fyn-Akt signaling in thrombocytopenia after allo-HSCT

Cross-Species scRNA-seq Finds Ideal Mouse Models for Aortic Dissection Mechanisms

Intratumoral bacterium Enterocloster bolteae promotes hepatocellular carcinoma progression by directly binding tumor cells

Ribonuclease 5/Angiogenin Suppresses Intestinal Tumor Initiation by Maintaining Crypt Homeostasis

Fibroblast‐Derived Microfibrillar‐Associated Protein 5 Exerts Cardioprotective Effects After Myocardial Infarction by Activating the NOTCH2 Signaling in Cardiomyocytes

Commensal enteric virome regulates intestinal carbohydrate digestion and absorption

WWP2 underlies ROS-induced granulosa cell apoptosis by promoting ubiquitination of BAK in polycystic ovary syndrome

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