历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Precision-engineered STING agonist nanoparticles enable coordinated mucosal-systemic immunity for durable pan-β-coronavirus protection
                        

产品名称：Sting-KO;hACE2-Tg

研究领域：广谱冠状病毒疫苗;STING激动剂;纳米粒;粘膜免疫;全身免疫;协同免疫保护

发表年份：2026 发表杂志：Nature Nanotechnology

                            
                            Hepatocyte-to-intestinal stem cell remote communication regulates blood glucose homeostasis
                        

产品名称：Alb-CreERT2

研究领域：血糖稳态;肝细胞-肠干细胞轴;器官间相互作用;代谢调节;肠上皮更新

发表年份：2026 发表杂志：Cell Metabolism

                            
                            Intermediate accumulated upon interruption of fatty acid oxidation flux promotes tumoral ferroptosis and improves immunotherapy
                        

产品名称：M-NSG

研究领域：肿瘤铁死亡;脂肪酸氧化;代谢中间产物;免疫治疗;脂质过氧化;代谢干预

发表年份：2026 发表杂志：Nature Communications

                            
                            Regulatory mechanism of the RNF168–SCCA1–MYH9 signaling axis in the response of ulcerative colitis
                        

产品名称：Rnf168-KO

研究领域：溃疡性结肠炎;肠粘膜屏障

发表年份：2026 发表杂志：JOURNAL OF GASTROENTEROLOGY

                            
                            TLE3,a transcriptional co-repressor, is dispensable for spermatogenesis and male fertility in mice
                        

产品名称：Tle3-Flox

研究领域：雄性生育力;转录辅抑制因子;生殖生物学

发表年份：2026 发表杂志：THERIOGENOLOGY

                            
                            AKAP1 enhances glycogen accumulation and hepatocarcinogenesis through YTHDF2-mediated G6PC mRNA decay
                        

产品名称：Akap1l-KO

研究领域：肝细胞癌;糖原代谢;m6A修饰

发表年份：2026 发表杂志：Signal Transduction and Targeted Therapy

                            
                            Engineered Nestin+ TSPC‐Derived Exosomes Promote Tendon Repair Via Metabolic Reprogramming
                        

产品名称：Nes-CreERT2

研究领域：肌腱修复;外泌体;代谢重编程;再生医学

发表年份：2026 发表杂志：Journal of Extracellular Vesicles

                            
                            Inhibiting fear memory recall-induced oligodendrogenesis rescues PTSD-like behaviors
                        

产品名称：mT(loxp)/mG(rox);MOG-DreERT

研究领域：创伤后应激障碍;恐惧记忆唤起;少突胶质细胞发生;髓鞘可塑性;记忆巩固;神经环路

发表年份：2026 发表杂志：MOLECULAR PSYCHIATRY

                            
                            CHST5 gene mutations contribute to high myopia by disrupting collagen fiber organization
                        

产品名称：Chst5-S126R

研究领域：高度近视;胶原纤维组织;硫酸化修饰;巩膜重塑;遗传学

发表年份：2026 发表杂志：Journal of Genetics and Genomics

                            
                            An NAG-Activatable Bioluminescent Probe for Sensitive Diagnosis of Acute Kidney Injury In Vivo and in Urine Samples
                        

产品名称：R26-CAGLuc-2A-EGFP

研究领域：急性肾损伤;生物发光探针;尿液诊断;体内成像;分子检测

发表年份：2026 发表杂志：ANALYTICAL CHEMISTRY

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Precision-engineered STING agonist nanoparticles enable coordinated mucosal-systemic immunity for durable pan-β-coronavirus protection

Hepatocyte-to-intestinal stem cell remote communication regulates blood glucose homeostasis

Intermediate accumulated upon interruption of fatty acid oxidation flux promotes tumoral ferroptosis and improves immunotherapy

Regulatory mechanism of the RNF168–SCCA1–MYH9 signaling axis in the response of ulcerative colitis

TLE3,a transcriptional co-repressor, is dispensable for spermatogenesis and male fertility in mice

AKAP1 enhances glycogen accumulation and hepatocarcinogenesis through YTHDF2-mediated G6PC mRNA decay

Engineered Nestin+ TSPC‐Derived Exosomes Promote Tendon Repair Via Metabolic Reprogramming

Inhibiting fear memory recall-induced oligodendrogenesis rescues PTSD-like behaviors

CHST5 gene mutations contribute to high myopia by disrupting collagen fiber organization

An NAG-Activatable Bioluminescent Probe for Sensitive Diagnosis of Acute Kidney Injury In Vivo and in Urine Samples

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