历年文献基因敲除小鼠_转基因小鼠定制

                            
                            SLC39A1 promotes pancreatic cancer metastasis by elevating intracellular zinc and activating the Src/FAK signaling pathway
                        

产品名称：KPC

研究领域：胰腺癌; 肿瘤转移

发表年份：2026 发表杂志：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

                            
                            TSG-6 Exacerbates Myocardial Ischemia-Reperfusion Injury by Activating NLRP3 Inflammasome and Regulating Macrophage Polarization
                        

产品名称：TSG6-Flox

研究领域：心肌缺血再灌注损伤; 巨噬细胞

发表年份：2026 发表杂志：Translational Research

                            
                            6-Shogaol inhibits HSCs activation and liver fibrosis by regulating glycolytic reprogramming via targeting HIF-1α
                        

产品名称：Hif1a-Flox

研究领域：肝纤维化; 代谢重编程

发表年份：2026 发表杂志：Chinese Medicine

LISS enables immune evasion of colorectal cancers irrespective of MSI status

产品名称：LISS-Flox

研究领域：结直肠癌; 免疫逃逸

发表年份：2026 发表杂志：Signal Transduction and Targeted Therapy

                            
                            WAT-to-BAT communication facilitates the sustained activation of BAT thermogenesis during cold exposure
                        

产品名称：IL33-KO

研究领域：脂肪组织; 产热

发表年份：2026 发表杂志：Cell Discovery

                            
                            Selective cellular localization of UHRF1 safeguards mammalian zygotic genome activation and early embryonic development
                        

产品名称：Uhrf1-Flox; Dnmt1-Flox

研究领域：胚胎发育

发表年份：2026 发表杂志：Cell Discovery

                            
                            IAR025, a novel anti-DLL3 x CD3-bispecific antibody, displays high antitumor efficacy in preclinical models of small-cell lung cancer
                        

产品名称：hCD3EDG

研究领域：小细胞肺癌; 抗肿瘤疗效

发表年份：2026 发表杂志：CANCER IMMUNOLOGY IMMUNOTHERAPY

                            
                            Byakangelicin alleviates metabolic dysfunction-associated steatohepatitis by selective inhibition of a non-canonical MTORC1 signaling pathway
                        

产品名称：Alb-CreERT2

研究领域：代谢功能障碍相关脂肪肝炎; 白当归素

发表年份：2026 发表杂志：Autophagy

                            
                            GPR161 contributes to macrophage glycolytic reprogramming via targeting C5aR1 in acute lung injury
                        

产品名称：R26-CreERT2; Lyz-Cre

研究领域：巨噬细胞; 急性肺损伤; 代谢重编程

发表年份：2026 发表杂志：CELLULAR & MOLECULAR BIOLOGY LETTERS

                            
                            Fn14 signalling participates in pristane-induced murine lupus through exacerbating oxidative stress
                        

产品名称：Fn14-KO

研究领域：系统性红斑狼疮; 氧化应激

发表年份：2026 发表杂志：BRITISH JOURNAL OF PHARMACOLOGY

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SLC39A1 promotes pancreatic cancer metastasis by elevating intracellular zinc and activating the Src/FAK signaling pathway

TSG-6 Exacerbates Myocardial Ischemia-Reperfusion Injury by Activating NLRP3 Inflammasome and Regulating Macrophage Polarization

6-Shogaol inhibits HSCs activation and liver fibrosis by regulating glycolytic reprogramming via targeting HIF-1α

LISS enables immune evasion of colorectal cancers irrespective of MSI status

WAT-to-BAT communication facilitates the sustained activation of BAT thermogenesis during cold exposure

Selective cellular localization of UHRF1 safeguards mammalian zygotic genome activation and early embryonic development

IAR025, a novel anti-DLL3 x CD3-bispecific antibody, displays high antitumor efficacy in preclinical models of small-cell lung cancer

Byakangelicin alleviates metabolic dysfunction-associated steatohepatitis by selective inhibition of a non-canonical MTORC1 signaling pathway

GPR161 contributes to macrophage glycolytic reprogramming via targeting C5aR1 in acute lung injury

Fn14 signalling participates in pristane-induced murine lupus through exacerbating oxidative stress

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