历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Mucosal-associated invariant T cells promote PDAC progression via TL1A–CSF-1 axis
                        

产品名称：Mr1-KO

研究领域：胰腺癌; 黏膜相关恒定T细胞

发表年份：2026 发表杂志：JOURNAL OF GASTROENTEROLOGY

                            
                            EGFR-Targeting IgG1 Antibody Enhances NK Cell-Mediated Tumor Killing in KRAS-Mutant Pancreatic Cancer
                        

产品名称：BALB/c Nude; M-NSG

研究领域：胰腺癌; 免疫治疗

发表年份：2026 发表杂志：MedComm

                            
                            Commensal Cutibacterium acnes-derived indolelactic acid safeguards skin barrier function through the aryl hydrocarbon receptor
                        

产品名称：K14-Cre

研究领域：皮肤屏障; 炎症性皮肤病

发表年份：2026 发表杂志：Cell Reports Medicine

                            
                            Semaglutide alleviates osteoarthritis independent of weight loss via GLP-1R–mediated activation of autophagy through AKT/mTOR inhibition
                        

产品名称：Glp1r-KO

研究领域：骨关节炎; 代谢调节

发表年份：2026 发表杂志：Journal of Orthopaedic Translation

                            
                            Targeting fibrillin-1 disrupts the fibrogenic niche formation and ameliorates kidney fibrosis
                        

产品名称：Cdh16-Cre; Fbn1-Flox

研究领域：肾脏纤维化; 肾损伤

发表年份：2026 发表杂志：Journal of Advanced Research

                            
                            Neuron-Derived MIF Engages VCAM1 to Fuel a Self-Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer
                        

产品名称：Mif-Flox; Nestin-CreERT2

研究领域：胃癌; 肿瘤转移

发表年份：2026 发表杂志：Advanced Science

                            
                            Combined inhibition of BETs and HDACs as a potential epigenetics-based therapy for malignant rhabdoid tumor
                        

产品名称：M-NSG

研究领域：肿瘤; 表观遗传

发表年份：2026 发表杂志：Cell Death & Disease

                            
                            Nrf2 deficiency converts the ESCC microenvironment into an immunologically active state via the GPX2-ICD-DC signaling path
                        

产品名称：Nrf2-Flox; K14-cre

研究领域：食管鳞癌; 肿瘤免疫

发表年份：2026 发表杂志：Journal of Translational Medicine

                            
                            Therapeutic targeting of AREL1 in hepatic stellate cells attenuates MASH-related liver fibrosis
                        

产品名称：lrat-Cre ; AREL1-Flox

研究领域：肝脏纤维化; MASH

发表年份：2026 发表杂志：Nature Communications

                            
                            Activation of microglial PPARγ by asperosaponin VI alleviates stress-induced depression and synaptic impairment
                        

产品名称：Pparg-Flox;Cx3cr1-CreER

研究领域：抑郁症; 神经精神

发表年份：2026 发表杂志：Journal of Advanced Research

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Mucosal-associated invariant T cells promote PDAC progression via TL1A–CSF-1 axis

EGFR-Targeting IgG1 Antibody Enhances NK Cell-Mediated Tumor Killing in KRAS-Mutant Pancreatic Cancer

Commensal Cutibacterium acnes-derived indolelactic acid safeguards skin barrier function through the aryl hydrocarbon receptor

Semaglutide alleviates osteoarthritis independent of weight loss via GLP-1R–mediated activation of autophagy through AKT/mTOR inhibition

Targeting fibrillin-1 disrupts the fibrogenic niche formation and ameliorates kidney fibrosis

Neuron-Derived MIF Engages VCAM1 to Fuel a Self-Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

Combined inhibition of BETs and HDACs as a potential epigenetics-based therapy for malignant rhabdoid tumor

Nrf2 deficiency converts the ESCC microenvironment into an immunologically active state via the GPX2-ICD-DC signaling path

Therapeutic targeting of AREL1 in hepatic stellate cells attenuates MASH-related liver fibrosis

Activation of microglial PPARγ by asperosaponin VI alleviates stress-induced depression and synaptic impairment

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