Ly6g-Cre-2A-tdTomato

品系全名

C57BL/6JSmo-Ly6gem2(iCre-P2A-tdTomato-polyA)Smoc

目录号

NM-KI-200219

品系状态

活体

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基因信息

基因名
Ly6g

基因曾用名

Gr1; Gr-1; Ly-6G

NCBI ID

546644

MGI ID

109440

Ensembl ID

ENSMUSG00000022582

Pubmed

Ly6g

人类同源基因

LY6G

品系描述

将iCre-P2A-tdTomato-polyA共表达结构插入到小鼠Ly6g基因起始密码子处。
应用领域：Cre工具鼠

验证数据

image.pngFig1. Cre mediated recombination in spleen of Ly6gCre-tdTomato/+;Rosa26zsGreen/+ mouse.

image.png

Fig2. Detection of tdTomato(red) and zsGreen(green) in various tissues of Ly6gCre-tdTomato/+;Rosa26zsGreen/+ mouse. Expression tissues include: spleen, thymus, colon. A few cells expressed in liver, stomach, kidney, small intestine and adrenal gland. Tissues that unexpressed include brain, spinal cord, eyeballs, heart, lung, salivary glands, brown fat, pituitary gland, pancreas, uterus and ovaries, muscle, skin. (5-week old, female) 

No obvious positive signals were detected in the tissue for tdTomato. (For more detailed information please contact our technical advisor.)

image.pngFig3. Detection of Ly6G and tdTomato expression on neutrophils in peripheral blood in WT and HE Ly6g-Cre-2A-tdTomato KI mice. 

发表文献 5篇

1. Cancer Metastasis Blockage by Exosome-Neutrophil Nanocoupler
发表年份：2026 来源杂志：Journal of the American Chemical Society

2. PIEZO1 mediates mechanical reprogramming of neutrophils for proangiogenic specialization in the lung
发表年份：2025 来源杂志：JOURNAL OF CLINICAL INVESTIGATION

3. Reciprocal Interaction with Neutrophils Facilitates Cutaneous Accumulation of Liposomes
发表年份：2024 来源杂志：ACS Nano

4. Inhibition of neutrophil swarming by type I interferon promotes intracellular bacterial evasion
发表年份：2024 来源杂志：Nature Communications

5. Spatiotemporal Analysis of Mesenchymal Stem Cells Fate Determination by Inflammatory Niche Following Soft Tissue Injury at a Single-Cell Level
发表年份：2024 来源杂志：Advanced Science

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