Cyp19a1-2A-CreERT2
品系全名
C57BL/6Smoc-Cyp19a1em1(2A-CreERT2)Smoc
目录号
NM-KI-251511
品系状态
活体
基因信息
基因名
Cyp19a1
品系描述
鉴定报告
下载验证数据
Fig1. CreERT2 mediated recombination in testicle of Cyp19a1CreERT2/+; Rosa26tdTomato/+ mouse.
Fig2. Detection of tdTomato(red) in various tissues of Cyp19a1CreERT2/+; Rosa26tdTomato/+ mouse.
Organs and tissues with tdTomato expression following tamoxifen induction include: brain, large intestine, salivary gland, reproductive system, and adrenal gland.
Organs and tissues without tdTomato expression following tamoxifen induction include:Small intestine, stomach, liver, lung, spleen, skin, pancreas, kidney, eyeball.(65-days old, male) (For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。
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