Thy1-CreERT2

Fig1. Detection of tdTomato expression on CD90+ cells in BM, spleen and blood. 

In tamoxifen-treated HE/HE Thy1-CreERT2/R26-CAG-LSL-tdTomato mice, most CD90+ cells were tdTomato+ in bone marrow (~70 %), spleen (~90 %) and blood (~95 %).

Fig2. Detection of CD90 expression on tdTomato+ cells in BM, spleen and blood. 

In HE/HE Thy1-CreERT2/R26-CAG-LSL-tdTomato mice, most tdTomato+ cells were CD90+ in bone marrow (~60 %), spleen (~90 %) and blood (66.5~89.4 %).

b

Fig3. CreERT2 mediated recombination in brain(Purkinje cell) of Thy1^CreERT2/+;Rosa26 ^tdTomato/+ mice

Fig4. Detection of tdTomato(red) in various tissues of Thy1^CreERT2/+;Rosa26 ^tdTomato/+ mouse. 

Organs and tissues with tdTomato expression following tamoxifen induction include: brain, spinal cord, large intestine, small intestine, stomach, liver, heart, lungs, salivary glands, spleen, skin, pancreas, reproductive system, adrenal glands, kidneys, thymus, and eyeballs.

Tissues with expression leakage in the uninduced group include: brain, salivary glands, skin, reproductive system, and eyes (retina).(119-days old, female and male) (For more detailed information please contact our technical advisor.)