历年文献基因敲除小鼠_转基因小鼠定制

                            
                            A Novel H2S Donor Suppresses Pilocarpine-Induced Seizures Through TREM2 Signaling
                        

产品名称：TREM2-KO

研究领域：神经; 癫痫

发表年份：2025 发表杂志：NEUROCHEMICAL RESEARCH

                            
                            Microglial TREM2 deficiency causes E/I imbalance and triggers ASD-like behaviors by altering potassium channel Kv1.3 activation
                        

产品名称：Trem2-Flox

研究领域：神经; 自闭症谱系障碍

发表年份：2025 发表杂志：NEUROBIOLOGY OF DISEASE

                            
                            Injury-induced Clusterin+ cardiomyocytes suppress inflammation and promote regeneration in neonatal and adult hearts by reprogramming macrophages
                        

产品名称：Rosa26-rox-stop-rox-tdTomato;R26-CAG-LSL-RSR-tdTomato-2A-DTR;Cpt1a-Flox;Clu-2A-DreERT2;R26-LSL-Clu-3xHA-2A-tdTomato;Gpnmb-CreERT2-2A-EGFP;Bmpr1a-Flox

研究领域：心肌细胞炎症及再生

发表年份：2025 发表杂志：Cell Stem Cell

                            
                            Fatty acid-binding protein 4 drives microglia-mediated neuroinflammation through promoting S100A9 expression and lipid droplet accumulation after intracerebral hemorrhage
                        

产品名称：FABP4-flox;TMEM119-CreERT2

研究领域：脑内出血; 神经炎症

发表年份：2025 发表杂志：Journal of Neuroinflammation

                            
                            Targeting the ac4C ‘Writer’ NAT10 enhances pancreatic cancer immunotherapy via dual modulation of CD8+ T cells and tumor cells
                        

产品名称：C57BL/6;BALB/c Nude

研究领域：胰腺癌;肿瘤微环境

发表年份：2025 发表杂志：Cell Death & Disease

                            
                            An injectable cisplatin hydrogel effectively suppresses tumors while preserving anti-infective immunity
                        

产品名称：C57BL/6

研究领域：药物释放系统; 顺铂

发表年份：2025 发表杂志：MATERIALS & DESIGN

MDMX reprograms glycolysis of hepatocellular carcinoma via 14-3-3γ/FOXO1

产品名称：Rosa26-CAG-LSL-mMdmx-P2A-zsGreen-polyA

研究领域：肝细胞癌; 代谢重编程

发表年份：2025 发表杂志：Cell Death Discovery

                            
                            Suppression of 6-pyruvoyl-tetrahydropterin synthase promotes remyelination in multiple sclerosis
                        

产品名称：Ptsf-Flox

研究领域：神经; 多发性硬化症

发表年份：2025 发表杂志：BMC Medicine

                            
                            Unraveling the reproductive toxicity mechanisms of emerging environmental contaminants 6:2 and 8:2 diPAPs in male mice: an integrated transcriptome-metabolome investigation
                        

产品名称：饲养繁育

研究领域：生殖毒性

发表年份：2025 发表杂志：ENVIRONMENTAL POLLUTION

                            
                            ESCRT-III Subunit CHMP4C Regulates Angiogenesis by Targeting Endocytic Trafficking of GSK3β
                        

产品名称：CHMP4C-KO

研究领域：缺血性疾病; 血管生成

发表年份：2025 发表杂志：FASEB JOURNAL

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A Novel H2S Donor Suppresses Pilocarpine-Induced Seizures Through TREM2 Signaling

Microglial TREM2 deficiency causes E/I imbalance and triggers ASD-like behaviors by altering potassium channel Kv1.3 activation

Injury-induced Clusterin+ cardiomyocytes suppress inflammation and promote regeneration in neonatal and adult hearts by reprogramming macrophages

Fatty acid-binding protein 4 drives microglia-mediated neuroinflammation through promoting S100A9 expression and lipid droplet accumulation after intracerebral hemorrhage

Targeting the ac4C ‘Writer’ NAT10 enhances pancreatic cancer immunotherapy via dual modulation of CD8+ T cells and tumor cells

An injectable cisplatin hydrogel effectively suppresses tumors while preserving anti-infective immunity

MDMX reprograms glycolysis of hepatocellular carcinoma via 14-3-3γ/FOXO1

Suppression of 6-pyruvoyl-tetrahydropterin synthase promotes remyelination in multiple sclerosis

Unraveling the reproductive toxicity mechanisms of emerging environmental contaminants 6:2 and 8:2 diPAPs in male mice: an integrated transcriptome-metabolome investigation

ESCRT-III Subunit CHMP4C Regulates Angiogenesis by Targeting Endocytic Trafficking of GSK3β

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