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An inflammatory checkpoint generated by IL1RN splicing offers therapeutic opportunity for KRAS mutant intrahepatic cholangiocarcinoma

产品名称：Ly6g-2A-DTRGFP

研究领域：肿瘤及肿瘤免疫;肝内胆管癌(iCCA)

发表年份：2023 发表杂志：Cancer Discovery

iNOS aggravates pressure overload-induced cardiac dysfunction via activation of the cytosolic-mtDNA-mediated cGAS-STING pathway

产品名称：Sting1-Flox

研究领域：自身免疫及炎症;无菌性炎症

发表年份：2023 发表杂志：Theranostics

Ceramide-1-phosphate alleviates high-altitude pulmonary edema by stabilizing circadian ARNTL-mediated mitochondrial dynamics

产品名称：CerKO

研究领域：自身免疫及炎症;高原肺水肿(HAPE)

发表年份：2023 发表杂志：Journal of Advanced Research

Alcohol reshapes a liver premetastatic niche for cancer by extra- and intrahepatic crosstalk-mediated immune evasion

产品名称：Il6-Luc-2A-EGFP

研究领域：肿瘤及肿瘤免疫;结肠癌、胰腺癌

发表年份：2023 发表杂志：MOLECULAR THERAPY

Comprehensive spatiotemporal mapping of single-cell lineages in developing mouse brain by CRISPR-based barcoding

产品名称：Pbx1-KO

研究领域：单细胞谱系特异性追踪(CREST)

发表年份：2023 发表杂志：NATURE METHODS

SARS-CoV-2 spike protein receptor-binding domain perturbates intracellular calcium homeostasis and impairs pulmonary vascular endothelial cells

产品名称：CAG-hACE2-IRES-Luc-Tg

研究领域：代谢心血管;肺血管内皮损伤

发表年份：2023 发表杂志：Signal Transduction and Targeted Therapy

Sequence-based drug design as a concept in computational drug design

产品名称：M-NSG

研究领域：其它;药物设计

发表年份：2023 发表杂志：Nature Communications

Targeting gut microbiota–derived kynurenine to predict and protect the remodeling of the pressure-overloaded young heart

产品名称：Ahr-KO

研究领域：代谢心血管;心力衰竭

发表年份：2023 发表杂志：Science Advances

α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure

产品名称：Ldha-Flox;Myh6-K1897R

研究领域：代谢心血管;心力衰竭

发表年份：2023 发表杂志：CELL RESEARCH

STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2

产品名称：M-NSG

研究领域：肿瘤及肿瘤免疫;先天免疫信号转接器STING

发表年份：2023 发表杂志：NATURE CELL BIOLOGY

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