历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH-Mutant Glioma
                        

产品名称：M-NSG

研究领域：胶质瘤;靶向治疗耐药性

发表年份：2025 发表杂志：Advanced Science

                            
                            Tumor-Derived Interleukin 35 Promotes Fibrosis in the Tumor Microenvironment of Pancreatic Cancer by Activating Pancreatic Stellate Cells
                        

产品名称：Ebi3-Flox;IL12a-Flox

研究领域：胰腺癌; 肿瘤微环境

发表年份：2025 发表杂志：Advanced Science

                            
                            RNA N6-methyladenosine reader protein YTHDF1 promotes plasma cell differentiation via IRF4 regulation in systemic lupus erythematosus
                        

产品名称：Ythdf1-Flox

研究领域：系统性红斑狼疮; m6A

发表年份：2025 发表杂志：EXPERIMENTAL AND MOLECULAR MEDICINE

                            
                            Hepatic hypertension on-a-chip identifies GPR116 as a hydrostatic pressure mechanosensor to regulate vascular injury in cirrhosis
                        

产品名称：Gpr116-flox;Cdh5-2A-CreERT2

研究领域：肝硬化; 门静脉高压

发表年份：2025 发表杂志：Science Advances

                            
                            AMSC-EVs attenuate acute kidney injury through TXNIP-IKKα/NFκB signaling-mediated renal CX3CR1+ macrophage polarization
                        

产品名称：R26-CAG-LSL-tdTomato-2A-DTR

研究领域：急性肾损伤; 细胞外囊泡

发表年份：2025 发表杂志：Stem Cell Research & Therapy

                            
                            Early growth response 2 activates MAF bZIP transcription factor F to protect β-cells from oxidative stress in type 1 diabetes
                        

产品名称：BALB/c

研究领域：1型糖尿病; 胰腺β细胞

发表年份：2025 发表杂志：TISSUE & CELL

                            
                            A Homozygous Mutation (c.241G > A, p.A81T) in the Calsequestrin-2 Causes Eye Defects in Zebrafish
                        

产品名称：Zebrafish

研究领域：眼科; 遗传学与发育

发表年份：2025 发表杂志：BIOCHEMICAL GENETICS

                            
                            Targeting formyl peptide receptor 1 reduces brain inflammation and neurodegeneration
                        

产品名称：hFPR1

研究领域：神经; 多发性硬化症

发表年份：2025 发表杂志：SCIENCE

                            
                            Heat shock protein DNAJA2 controls insulin signaling and glucose homeostasis by preventing spontaneous insulin receptor endocytosis
                        

产品名称：Dnaja2-Flox

研究领域：葡萄糖代谢; 2型糖尿病

发表年份：2025 发表杂志：Nature Communications

                            
                            Qushi Huayu decoction alleviates NAFLD in mice by regulating gut microbiota homeostasis in the gut-liver axis via the pregnane X receptor
                        

产品名称：Pxr-KO

研究领域：代谢功能障碍相关脂肪性肝病

发表年份：2025 发表杂志：EUROPEAN JOURNAL OF PHARMACOLOGY

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Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH-Mutant Glioma

Tumor-Derived Interleukin 35 Promotes Fibrosis in the Tumor Microenvironment of Pancreatic Cancer by Activating Pancreatic Stellate Cells

RNA N6-methyladenosine reader protein YTHDF1 promotes plasma cell differentiation via IRF4 regulation in systemic lupus erythematosus

Hepatic hypertension on-a-chip identifies GPR116 as a hydrostatic pressure mechanosensor to regulate vascular injury in cirrhosis

AMSC-EVs attenuate acute kidney injury through TXNIP-IKKα/NFκB signaling-mediated renal CX3CR1+ macrophage polarization

Early growth response 2 activates MAF bZIP transcription factor F to protect β-cells from oxidative stress in type 1 diabetes

A Homozygous Mutation (c.241G > A, p.A81T) in the Calsequestrin-2 Causes Eye Defects in Zebrafish

Targeting formyl peptide receptor 1 reduces brain inflammation and neurodegeneration

Heat shock protein DNAJA2 controls insulin signaling and glucose homeostasis by preventing spontaneous insulin receptor endocytosis

Qushi Huayu decoction alleviates NAFLD in mice by regulating gut microbiota homeostasis in the gut-liver axis via the pregnane X receptor

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