历年文献基因敲除小鼠_转基因小鼠定制

                            
                            PACS-2 Mitigates NPSC Apoptosis and Intervertebral Disc Degeneration by Preserving MAM Integrity via the SP1/LRRK2/Mfn2 Axis
                        

产品名称：Pacs2-KO

研究领域：椎间盘退行性变

发表年份：2025 发表杂志：Advanced Science

                            
                            Estrogen receptor β deficiency increases the susceptibility to ulcerative colitis by inducing mitochondrial fission and consequently accelerating senescence of colonic epithelial cells
                        

产品名称：ERβ-KO

研究领域：溃疡性结肠炎

发表年份：2025 发表杂志：Redox Biology

                            
                            SETD7 exacerbates diabetic nephropathy through activating A2B receptor-JAK2/STAT3 pathway
                        

产品名称：Setd7-KO

研究领域：糖尿病肾病

发表年份：2025 发表杂志：Cell and Bioscience

                            
                            Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis
                        

产品名称：C57BL/6

研究领域：肿瘤相关脂肪细胞; 肿瘤免疫

发表年份：2025 发表杂志：Cell Reports

                            
                            PIEZO1‐Primary Cilia Axis Mediates Compressive Stress‐Induced Growth Plate Degeneration and Ossification in Adolescent Idiopathic Scoliosis
                        

产品名称：Ift88-Flox;Col2a1‐CreERT

研究领域：青少年特发性脊柱侧弯

发表年份：2025 发表杂志：JOR Spine

                            
                            Neutralizing antibodies against Chikungunya virus and structural elucidation of their mechanism of action
                        

产品名称：Ifnar1-KO

研究领域：病毒感染; 基孔肯雅病毒

发表年份：2025 发表杂志：Nature Communications

                            
                            JMJD3 upregulates ALOX5 to drive malignancy and concomitant ferroptosis sensitivity in gastric cancer
                        

产品名称：M-NSG

研究领域：胃癌; 化疗耐药性; 铁死亡

发表年份：2025 发表杂志：Cell Death & Disease

                            
                            Sino-C, a novel sinomenine derivative, induces cell death by disrupting cholesterol homeostasis in colorectal cancer cells
                        

产品名称：BALB/c Nude

研究领域：结直肠癌; 胆固醇稳态

发表年份：2025 发表杂志：ACTA PHARMACOLOGICA SINICA

                            
                            The lysosomal cysteine protease cathepsin L promotes stemness and multidrug resistance of non-small cell lung cancer by targeting HGF activator
                        

产品名称：BALB/c Nude

研究领域：肿瘤; 非小细胞肺癌

发表年份：2025 发表杂志：MOLECULAR AND CELLULAR BIOCHEMISTRY

                            
                            Gut-initiated mucosal and systemic immunity against SARS-CoV-2 via an oral hyaluronic acid/chitosan vaccine coacervate
                        

产品名称：CAG-hACE2-IRES-Luc-Tg

研究领域：COVID-19; 口服疫苗递送

发表年份：2025 发表杂志：JOURNAL OF CONTROLLED RELEASE

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PACS-2 Mitigates NPSC Apoptosis and Intervertebral Disc Degeneration by Preserving MAM Integrity via the SP1/LRRK2/Mfn2 Axis

Estrogen receptor β deficiency increases the susceptibility to ulcerative colitis by inducing mitochondrial fission and consequently accelerating senescence of colonic epithelial cells

SETD7 exacerbates diabetic nephropathy through activating A2B receptor-JAK2/STAT3 pathway

Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis

PIEZO1‐Primary Cilia Axis Mediates Compressive Stress‐Induced Growth Plate Degeneration and Ossification in Adolescent Idiopathic Scoliosis

Neutralizing antibodies against Chikungunya virus and structural elucidation of their mechanism of action

JMJD3 upregulates ALOX5 to drive malignancy and concomitant ferroptosis sensitivity in gastric cancer

Sino-C, a novel sinomenine derivative, induces cell death by disrupting cholesterol homeostasis in colorectal cancer cells

The lysosomal cysteine protease cathepsin L promotes stemness and multidrug resistance of non-small cell lung cancer by targeting HGF activator

Gut-initiated mucosal and systemic immunity against SARS-CoV-2 via an oral hyaluronic acid/chitosan vaccine coacervate

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