历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Inhibiting IP6K1 confers atheroprotection by elevating circulating apolipoprotein A-I
                        

产品名称：Apoa1-KO

研究领域：代谢心血管;动脉粥样硬化保护

发表年份：2024 发表杂志：METABOLISM-CLINICAL AND EXPERIMENTAL

Dysregulation in keratinocytes drives systemic lupus erythematosus onset

产品名称：Pparg-Flox;Krt5-creERT2;Itgax-DTR

研究领域：自身免疫及炎症;系统性红斑狼疮

发表年份：2024 发表杂志：Cellular & Molecular Immunology

                            
                            Tumor-derived miR-9-5p-loaded EVs regulate cholesterol homeostasis to promote breast cancer liver metastasis in mice
                        

产品名称：Ch25h-Flox;M-NSG

研究领域：肿瘤及肿瘤免疫;乳腺癌肝转移

发表年份：2024 发表杂志：Nature Communications

Ultrasound Control of Genomic Regulatory Toolboxes for Cancer Immunotherapy

产品名称：M-NSG

研究领域：肿瘤及肿瘤免疫;癌症免疫治疗

发表年份：2024 发表杂志：Nature Communications

                            
                            Specific surface-modified iron oxide nanoparticles trigger complement-dependent innate and adaptive antileukaemia immunity
                        

产品名称：M-NSG

研究领域：肿瘤及肿瘤免疫;抗白血病免疫

发表年份：2024 发表杂志：Nature Communications

                            
                            Purinergic signaling by TCRαβ+ double-negative T regulatory cells ameliorates liver ischemia-reperfusion injury
                        

产品名称：Adora2a-KO

研究领域：自身免疫及炎症;肝缺血-再灌注损伤 (HIRI)

发表年份：2024 发表杂志：Science Bulletin

                            
                            RNF144A inhibits autophagy by targeting BECN1 for degradation during L. monocytogenes infection
                        

产品名称：rnf144a-KO

研究领域：自身免疫及炎症;单核细胞增生李斯特菌

发表年份：2024 发表杂志：Autophagy

                            
                            Dural Tregs driven by astrocytic IL-33 mitigate depression through the EGFR signals in mPFC neurons
                        

产品名称：Il33-KO;Il1rl1-KO

研究领域：神经;抑郁症

发表年份：2024 发表杂志：CELL DEATH AND DIFFERENTIATION

                            
                            YOD1 regulates microglial homeostasis by deubiquitinating MYH9 to promote the pathogenesis of Alzheimer’s disease
                        

产品名称：Yod1-KO

研究领域：神经;阿尔茨海默病

发表年份：2024 发表杂志：Acta Pharmaceutica Sinica B

                            
                            Facilitation of mucosal healing by estrogen receptor β in ulcerative colitis through suppression of branched-chain amino acid transport and subsequent triggering of autophagy in colonic epithelial cells
                        

产品名称：ERβ-KO

研究领域：自身免疫及炎症;溃疡性结肠炎 (UC)

发表年份：2024 发表杂志：Acta Pharmaceutica Sinica B

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Inhibiting IP6K1 confers atheroprotection by elevating circulating apolipoprotein A-I

Dysregulation in keratinocytes drives systemic lupus erythematosus onset

Tumor-derived miR-9-5p-loaded EVs regulate cholesterol homeostasis to promote breast cancer liver metastasis in mice

Ultrasound Control of Genomic Regulatory Toolboxes for Cancer Immunotherapy

Specific surface-modified iron oxide nanoparticles trigger complement-dependent innate and adaptive antileukaemia immunity

Purinergic signaling by TCRαβ+ double-negative T regulatory cells ameliorates liver ischemia-reperfusion injury

RNF144A inhibits autophagy by targeting BECN1 for degradation during L. monocytogenes infection

Dural Tregs driven by astrocytic IL-33 mitigate depression through the EGFR signals in mPFC neurons

YOD1 regulates microglial homeostasis by deubiquitinating MYH9 to promote the pathogenesis of Alzheimer’s disease

Facilitation of mucosal healing by estrogen receptor β in ulcerative colitis through suppression of branched-chain amino acid transport and subsequent triggering of autophagy in colonic epithelial cells

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