历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Bioinspired IgM-Mimetic Polyvalent Aptamer-Albumin Nanoplatform for Targeted Intravesical Therapy of Bladder Cancer
                        

产品名称：MB-49

研究领域：膀胱癌; 纳米平台; 适配体; 膀胱内灌注治疗

发表年份：2026 发表杂志：Small

                            
                            MTFR1L protects the heart from Ischemia–Reperfusion injury via dual mitochondrial mechanisms
                        

产品名称：Mtfr1l-KO

研究领域：心肌缺血再灌注损伤; 线粒体

发表年份：2026 发表杂志：Research

                            
                            Regulator of Calcineurin 1 Aggravates Tubular Epithelial Cell Injury in Diabetic Mice Through Promoting Liver Kinase B1 Ubiquitination
                        

产品名称：Cdh16-Cre

研究领域：糖尿病肾小管损伤; 钙调磷酸酶调节因子1; LKB1泛素化

发表年份：2026 发表杂志：FASEB JOURNAL

                            
                            TREM2 sustains glucose metabolic homeostasis to drive antibacterial defense during sepsis
                        

产品名称：Gsdmd-KO

研究领域：脓毒症; 葡萄糖代谢稳态

发表年份：2026 发表杂志：iScience

                            
                            Phthalate mixtures and pregnancy loss: Linking MCNP exposure with placental dysfunction via epidemiologic and in vivo evidence
                        

产品名称：ICR

研究领域：环境与生殖健康; 邻苯二甲酸酯混合物; 流产; 胎盘功能障碍

发表年份：2026 发表杂志：REPRODUCTIVE TOXICOLOGY

                            
                            Cars2-Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2
                        

产品名称：Cars2-Flox

研究领域：棕色脂肪; 半胱氨酸代谢; 蛋白质过硫化

发表年份：2026 发表杂志：Advanced Science

                            
                            A bispecific nanobody-drug conjugate targeting TROP2 and c-Met for low-concentration, single-dose treatment of pancreatic cancer
                        

产品名称：M-NSG

研究领域：胰腺癌; 双特异性纳米抗体-药物偶联物

发表年份：2026 发表杂志：Cell Reports Medicine

                            
                            Teriflunomide modulates the PD-1/PD-L1 axis and enhances antitumor immunity in colorectal cancer
                        

产品名称：hPD-1

研究领域：结直肠癌; PD-1/PD-L1; 特立氟胺; 抗肿瘤免疫

发表年份：2026 发表杂志：Oncogenesis

                            
                            Galactose-decorated lipid nanoparticle-mediated delivery of a selective NLRP3 inhibitor attenuates hepatic inflammation in metabolic dysfunction-associated steatotic liver disease
                        

产品名称：BALB/c

研究领域：代谢功能障碍相关脂肪性肝病; 脂质纳米颗粒; NLRP3抑制剂; 半乳糖修饰

发表年份：2026 发表杂志：Journal of Materials Chemistry B

                            
                            P2 X 7 receptor deficiency ameliorates high-fat-induced cardiac remodeling by improving oxidative stress through PI3K/AKT/GSK3β-mediated regulation of Nrf2
                        

产品名称：P2×7R-KO

研究领域：肥胖相关心脏重构; P2X7受体; 氧化应激

发表年份：2026 发表杂志：JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

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Bioinspired IgM-Mimetic Polyvalent Aptamer-Albumin Nanoplatform for Targeted Intravesical Therapy of Bladder Cancer

MTFR1L protects the heart from Ischemia–Reperfusion injury via dual mitochondrial mechanisms

Regulator of Calcineurin 1 Aggravates Tubular Epithelial Cell Injury in Diabetic Mice Through Promoting Liver Kinase B1 Ubiquitination

TREM2 sustains glucose metabolic homeostasis to drive antibacterial defense during sepsis

Phthalate mixtures and pregnancy loss: Linking MCNP exposure with placental dysfunction via epidemiologic and in vivo evidence

Cars2-Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

A bispecific nanobody-drug conjugate targeting TROP2 and c-Met for low-concentration, single-dose treatment of pancreatic cancer

Teriflunomide modulates the PD-1/PD-L1 axis and enhances antitumor immunity in colorectal cancer

Galactose-decorated lipid nanoparticle-mediated delivery of a selective NLRP3 inhibitor attenuates hepatic inflammation in metabolic dysfunction-associated steatotic liver disease

P2 X 7 receptor deficiency ameliorates high-fat-induced cardiac remodeling by improving oxidative stress through PI3K/AKT/GSK3β-mediated regulation of Nrf2

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