历年文献基因敲除小鼠_转基因小鼠定制

                            
                            COUP-TFII Promotes Macrophage-Myofibroblast Transition by Attenuating HIF-1α-Mediated Glycolysis
                        

产品名称：Lepr-g.G109052T

研究领域：器官纤维化; 巨噬-肌成纤维细胞转化; 糖酵解

发表年份：2026 发表杂志：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

                            
                            Protocol for genetic manipulation of cervical lymph node-innervating nociceptive neurons in mice via retrograde viral tracing
                        

产品名称：C57BL/6

研究领域：神经科学; 伤害性神经元; 颈淋巴结; 逆行病毒示踪

发表年份：2026 发表杂志：STAR Protocols

Targeting NK cell CLEC12B enhances cancer immunotherapy

产品名称：Clec12b-KO; Clec12b-Flox; M-NSG

研究领域：肿瘤免疫治疗; NK细胞

发表年份：2026 发表杂志：NATURE IMMUNOLOGY

                            
                            Estrogen receptor β deficiency increases susceptibility to sepsis through metabolic reprogramming-induced macrophage pyroptosis
                        

产品名称：Esr2-KO

研究领域：脓毒症; 雌激素受体β; 代谢重编程; 巨噬细胞焦亡

发表年份：2026 发表杂志：JOURNAL OF CLINICAL INVESTIGATION

                            
                            TRIM21 Exacerbates Ischemic Brain Injury by Promoting Astrocyte-Mediated Neuroinflammation via K63-Linked Ubiquitination of MDA5
                        

产品名称：Trim21-KO

研究领域：缺血性脑卒中; 星形胶质细胞; 神经炎症; MDA5泛素化

发表年份：2026 发表杂志：Research

                            
                            Macrophage RNA polymerase II subunit 5-mediating protein deficiency exacerbates kidney inflammation and fibrosis
                        

产品名称：LysM-Cre; RMP-Flox

研究领域：肾脏炎症与纤维化; 巨噬细胞

发表年份：2026 发表杂志：INFLAMMATION RESEARCH

                            
                            Hepatocyte specific Rab27a knockout aggravates metabolic dysfunction associated fatty liver disease
                        

产品名称：Alb-Cre

研究领域：代谢相关脂肪性肝病; 肝细胞特异性敲除

发表年份：2026 发表杂志：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

                            
                            PAK5-Mediated Suppression of β-Hydroxybutyrate Production Promotes Breast Cancer Metastasis and Can Be Overcome with Ketogenic Diet
                        

产品名称：Pak5-KO

研究领域：乳腺癌; 肿瘤转移; 生酮饮食

发表年份：2026 发表杂志：CANCER RESEARCH

                            
                            BM-derived mesenchymal stem cell microvesicles protect enteric neural precursor cells and alleviate diabetes-associated enteric neuropathy
                        

产品名称：Nestin-creERT2; R26-CAG-RSR-LSL-DTRGFP-WPRE; Ngfr-2A-DreERT2

研究领域：糖尿病肠神经病变; 间充质干细胞; 微囊泡; 神经前体细胞保护

发表年份：2026 发表杂志：JOURNAL OF CLINICAL INVESTIGATION

                            
                            Nanobowl-supported liposomes enhance paclitaxel delivery by improving loading stability and modulating protein corona effect
                        

产品名称：4T1-luc

研究领域：药物递送系统; 脂质体; 紫杉醇; 蛋白冠效应

发表年份：2026 发表杂志：Nano Today

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COUP-TFII Promotes Macrophage-Myofibroblast Transition by Attenuating HIF-1α-Mediated Glycolysis

Protocol for genetic manipulation of cervical lymph node-innervating nociceptive neurons in mice via retrograde viral tracing

Targeting NK cell CLEC12B enhances cancer immunotherapy

Estrogen receptor β deficiency increases susceptibility to sepsis through metabolic reprogramming-induced macrophage pyroptosis

TRIM21 Exacerbates Ischemic Brain Injury by Promoting Astrocyte-Mediated Neuroinflammation via K63-Linked Ubiquitination of MDA5

Macrophage RNA polymerase II subunit 5-mediating protein deficiency exacerbates kidney inflammation and fibrosis

Hepatocyte specific Rab27a knockout aggravates metabolic dysfunction associated fatty liver disease

PAK5-Mediated Suppression of β-Hydroxybutyrate Production Promotes Breast Cancer Metastasis and Can Be Overcome with Ketogenic Diet

BM-derived mesenchymal stem cell microvesicles protect enteric neural precursor cells and alleviate diabetes-associated enteric neuropathy

Nanobowl-supported liposomes enhance paclitaxel delivery by improving loading stability and modulating protein corona effect

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