Col1a1-IRES-EGFP-IRES-MerCreMer

品系全名

C57BL/6JSmo-Col1a1em1(IRES-EGFP-IRES-MerCreMer)Smoc

目录号

NM-KI-240492

品系状态

活体

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基因信息

基因名
Col1a1

基因曾用名

Cola1; Mov13; Cola-1; Mov-13; Col1a-1

染色体位置

11

NCBI ID

12842

MGI ID

88467

Ensembl ID

ENSMUSG00000001506

Pubmed

Col1a1

人类同源基因

COL1A1

品系描述

The IRES-EGFP-IRES-MerCreMer expression cassette was knocked into the Col1a1 gene stop codon site. The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

鉴定报告

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验证数据

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Fig1. Cre mediated recombination in femur of Col1a1MerCreMer/+;Rosa26tdTomato/+ mouse. 

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Fig2. Cre mediated recombination in skull of Col1a1MerCreMer/+;Rosa26tdTomato/+ mouse. 

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Fig3. Detection of EGFP(green) and tdTomato(red) in various tissues of Col1a1MerCreMer/+;Rosa26tdTomato/+ mouse. The tissues expressing both tdTomato and EGFP include: bone, skull, teeth, eye, lung, stomach, salivary gland, brown adipose tissue, adrenal gland, kidney, small intestine, large intestine, epididymis, and thymus.

The tissues expressing tdTomato include: brain, spinal cord, heart, pancreas, spleen, muscle, skin, and pituitary gland.

In the control group, tdTomato shows minimal leaky expression in: eye, adrenal gland, bone, teeth, epididymis, skin, and thymus.(83-days old, male) (For more detailed information please contact our technical advisor.) 



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