BALB/c Nude

品系全名

BALB/cAnSmoc-Foxn1nu/Smoc

目录号

SM-014

品系状态

活体

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品系描述

BALB/c背景下Foxn1基因纯合突变，裸鼠是快速生长的肿瘤细胞系的理想宿主，但部分细胞系在裸鼠上难以成瘤，如血液瘤细胞系、乳腺癌细胞系、原代细胞等。裸鼠无毛，更容易直观的评估皮下肿瘤的生长情况。

验证数据

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Fig1. Body weight growth curve of BALB/c Nude (n=780)

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Fig2. Complete deletion of T, B cells of BALB/c Nude. 

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Fig3. Subcutaneous xenograft tumor growth in BALB/c Nude. 

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Fig4. Blood routine tests in BALB/c Nude.

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Fig5. Blood biochemistry in BALB/c Nude.

Table 1. BALB/c Nude xenograft cell lines

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发表文献 18篇

1. RNA target-independent non-canonical activation (RINCA) of Cas13 trans-nuclease activity
发表年份：2025 来源杂志：Science Bulletin

2. Sino-C, a novel sinomenine derivative, induces cell death by disrupting cholesterol homeostasis in colorectal cancer cells
发表年份：2025 来源杂志：ACTA PHARMACOLOGICA SINICA

3. The lysosomal cysteine protease cathepsin L promotes stemness and multidrug resistance of non-small cell lung cancer by targeting HGF activator
发表年份：2025 来源杂志：MOLECULAR AND CELLULAR BIOCHEMISTRY

4. VDAC1 as prognostic marker and therapeutic target in lung adenocarcinoma: a study integrating bioinformatics and experimental validation
发表年份：2025 来源杂志：Discover Oncology

5. Acevaltrate as a novel ferroptosis inducer with dual targets of PCBP1/2 and GPX4 in colorectal cancer
发表年份：2025 来源杂志：Signal Transduction and Targeted Therapy

6. Targeting the ac4C ‘Writer’ NAT10 enhances pancreatic cancer immunotherapy via dual modulation of CD8+ T cells and tumor cells
发表年份：2025 来源杂志：Cell Death & Disease

7. BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism
发表年份：2024 来源杂志：Cell Host & Microbe

8. Acetate utilization promotes hormone therapy resistance in prostate cancer through neuroendocrine differentiation
发表年份：2024 来源杂志：DRUG RESISTANCE UPDATES

9. Effect of Bioactive Black Phosphorus Nanomaterials on Cancer-Associated Fibroblast Heterogeneity in Pancreatic Cancer
发表年份：2024 来源杂志：ACS Nano

10. Dual Inhibition of CDK4/6 and CDK7 Suppresses Triple-Negative Breast Cancer Progression via Epigenetic Modulation of SREBP1-Regulated Cholesterol Metabolism
发表年份：2024 来源杂志：Advanced Science

11. Aspirin-Mediated Acetylation of SIRT1 Maintains Intestinal Immune Homeostasis
发表年份：2024 来源杂志：Advanced Science

12. A STT3A-dependent PD-L1 glycosylation modification mediated by GMPS drives tumor immune evasion in hepatocellular carcinoma
发表年份：2024 来源杂志：CELL DEATH AND DIFFERENTIATION

13. Cuproptosis and Serine Metabolism Blockade Triggered by Copper-Based Prussian Blue Nanomedicine for Enhanced Tumor Therapy
发表年份：2024 来源杂志：Small

14. Exosome-derived circCCAR1 promotes CD8 + T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma
发表年份：2023 来源杂志：Molecular Cancer

15. Targeted therapy of central nervous system acute lymphoblastic leukemia with an integrin α6-targeted self-assembling proapoptotic nanopeptide
发表年份：2023 来源杂志：Engineering

16. Epitranscriptic regulation of HRAS by N6-methyladenosine drives tumor progression
发表年份：2023 来源杂志：PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

17. Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1
发表年份：2022 来源杂志：Nature Communications

18. RNA-binding protein RBM24 represses colorectal tumourigenesis by stabilising PTEN mRNA
发表年份：2021 来源杂志：Clinical and Translational Medicine

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