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Downregulation of neuronal DRD2 drives microglia synaptic pruning and results in cognitive deficits by promoting CCL2 release in a rat model of chronic migraine

产品名称:Drd2-KO

研究领域:慢性偏头痛; 小胶质细胞

发表年份:2026 发表杂志:JOURNAL OF HEADACHE AND PAIN

PPARγ in microglia helps protect adolescent male mice from harmful effects of stress during early development

产品名称:Pparg-Flox; Cx3cr1-CreERT2

研究领域:小胶质细胞; 突触可塑性

发表年份:2026 发表杂志:BRAIN BEHAVIOR AND IMMUNITY

UHRF1 deficiency exacerbates intestinal inflammation by epigenetic modulation of NPY1R gene methylation

产品名称:Uhrf1-Flox

研究领域:甲基化; 炎症性肠病(

发表年份:2026 发表杂志:JCI Insight

TREM2 Facilitates Myelin Debris Clearance but Exacerbates Chronic Inflammation and Fibrosis After Spinal Cord Injury

产品名称:Trem2-KO

研究领域:脊髓损伤

发表年份:2026 发表杂志:CNS Neuroscience & Therapeutics

Minnelide ameliorates Col4a5+/− mice by upregulating Col4a5 and alleviating endoplasmic reticulum stress

产品名称:Col4a5-R471X

研究领域:Alport综合征

发表年份:2026 发表杂志:Frontiers in Pharmacology

Estrogen regulates cognitive function in APP/PS1 female mice via modulation of IDO1-mediated Trp/Kyn metabolism through ERβ

产品名称:APP/PS1

研究领域:阿尔茨海默病

发表年份:2026 发表杂志:HORMONES AND BEHAVIOR

CEACAM6 silencing suppresses tumour growth and sensitises cholangiocarcinoma to cisplatin

产品名称:BALB/c Nude

研究领域:胆管癌; 肿瘤治疗; 化疗增敏

发表年份:2026 发表杂志:Clinical and Translational Discovery

RNF26 regulating tumor immunogenicity of hepatocellular carcinoma by degrading GRP78 and instigating ER stress

产品名称:HBC-tg

研究领域:肝细胞癌; 免疫抑制

发表年份:2026 发表杂志:DRUG RESISTANCE UPDATES

Biomimetic SIRPα–CAR Engineering for In Situ Macrophage Reprogramming and Potent Solid Tumor Immunotherapy

产品名称:MC38–hCD47

研究领域:细胞免疫疗法; 基于SIRPα的嵌合抗原受体

发表年份:2026 发表杂志:ADVANCED FUNCTIONAL MATERIALS

ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC-I Antigen Presentation That Promotes Tumor Immune Evasion

产品名称:M-NSG

研究领域:肿瘤细胞焦亡和抗原呈递

发表年份:2026 发表杂志:Advanced Science

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