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Piezo1 Upregulation in Monocyte-Derived Macrophages Impairs Post-Myocardial Infarction Cardiac Repair via Defective Efferocytosis and Enhanced Ferroptosis

产品名称：Lyz2-Cre

研究领域：心肌梗死; 巨噬细胞

发表日期：2025-11-10 发表杂志：Advanced Science

Loss of Slc39a5 in α-cells impairs glucose metabolism by chronically increasing glucagon

产品名称：Slc39a5-Flox

研究领域：葡萄糖代谢; 2型糖尿病

发表日期：2025-11-10 发表杂志：Journal of Advanced Research

E3 ligase CHIP restoration facilitates the effect of α1-adrenoceptor blockage on alleviating lipopolysaccharide-caused cardiac fibrosis via downregulating TGF-BR1 expression and Smad2/3 activation

产品名称：Chip-KO

研究领域：败血症; 心肌纤维化

发表日期：2025-11-10 发表杂志：Molecular Biomedicine

Genetic variants in HELB contribute to premature ovarian insufficiency and early age of natural menopause

产品名称：Helb-D112Y

研究领域：早发性卵巢功能不全

发表日期：2025-11-10 发表杂志：JCI Insight

A Novel H2S Donor Suppresses Pilocarpine-Induced Seizures Through TREM2 Signaling

产品名称：TREM2-KO

研究领域：神经; 癫痫

发表日期：2025-11-10 发表杂志：NEUROCHEMICAL RESEARCH

Microglial TREM2 deficiency causes E/I imbalance and triggers ASD-like behaviors by altering potassium channel Kv1.3 activation

产品名称：Trem2-Flox

研究领域：神经; 自闭症谱系障碍

发表日期：2025-11-08 发表杂志：NEUROBIOLOGY OF DISEASE

Injury-induced Clusterin+ cardiomyocytes suppress inflammation and promote regeneration in neonatal and adult hearts by reprogramming macrophages

产品名称：Rosa26-rox-stop-rox-tdTomato;R26-CAG-LSL-RSR-tdTomato-2A-DTR;Cpt1a-Flox;Clu-2A-DreERT2;R26-LSL-Clu-3xHA-2A-tdTomato;Gpnmb-CreERT2-2A-EGFP;Bmpr1a-Flox

研究领域：心肌细胞炎症及再生

发表日期：2025-11-07 发表杂志：Cell Stem Cell

Fatty acid-binding protein 4 drives microglia-mediated neuroinflammation through promoting S100A9 expression and lipid droplet accumulation after intracerebral hemorrhage

产品名称：FABP4-flox;TMEM119-CreERT2

研究领域：脑内出血; 神经炎症

发表日期：2025-11-07 发表杂志：Journal of Neuroinflammation

Targeting the ac4C ‘Writer’ NAT10 enhances pancreatic cancer immunotherapy via dual modulation of CD8+ T cells and tumor cells

产品名称：C57BL/6;BALB/c Nude

研究领域：胰腺癌;肿瘤微环境

发表日期：2025-11-07 发表杂志：Cell Death & Disease

An injectable cisplatin hydrogel effectively suppresses tumors while preserving anti-infective immunity

产品名称：C57BL/6

研究领域：药物释放系统; 顺铂

发表日期：2025-11-07 发表杂志：MATERIALS & DESIGN

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