历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Fibrous periosteum repairs bone fracture and maintains the healed bone throughout mouse adulthood
                        

产品名称：Osx-dre;Col1a1-BFP;Pdgfra-CreERT2;IR1:Rosa-CAG-loxp-rox-STOP-loxp-zsGreen-rox-tdTomato

研究领域：其它;纤维层骨膜细胞(FL-PCs)和骨干/祖细胞(SSPCs)

发表年份：2024 发表杂志：DEVELOPMENTAL CELL

                            
                            Defective prelamin A processing promotes unconventional necroptosis driven by nuclear RIPK1
                        

产品名称：Zmpste24-KO

研究领域：自身免疫及炎症;prelamin A积累类早老性疾病

发表年份：2024 发表杂志：NATURE CELL BIOLOGY

                            
                            Nuclear microRNA-mediated transcriptional control determines adult microglial homeostasis and brain function
                        

产品名称：Tmem119-2A-CreERT2

研究领域：

发表年份：2024-03-26 发表杂志：Cell Reports

                            
                            Restoring T and B cell generation in X-linked severe combined immunodeficiency mice through hematopoietic stem cells adenine base editing
                        

产品名称：-

研究领域：

发表年份：2024 发表杂志：MOLECULAR THERAPY

                            
                            The chemerin-CMKLR1 axis in keratinocytes impairs innate host defense against cutaneous Staphylococcus aureus infection
                        

产品名称：Cmklr1-Flox;Rarres2-Tg

研究领域：自身免疫及炎症;金黄色葡萄球菌感染

发表年份：2024 发表杂志：Cellular & Molecular Immunology

                            
                            Restoring T and B cell generation in X-linked severe combined immunodeficiency mice through hematopoietic stem cells adenine base editing
                        

产品名称：hIL2RG;Il2rg-KO;M-NSG

研究领域：自身免疫及炎症;造血干细胞/祖细胞(HSPCs)的碱基编辑

发表年份：2024 发表杂志：MOLECULAR THERAPY

                            
                            HDAC6-dependent deacetylation of NGF dictates its ubiquitination and maintains primordial follicle dormancy
                        

产品名称：M-NSG

研究领域：自身免疫及炎症;乙酰化酶6 (HDAC6)

发表年份：2024 发表杂志：Theranostics

Serotonergic modulation of vigilance states in zebrafish and mice

产品名称：Slc6a4-Cre

研究领域：神经;5-羟色胺驱动机制

发表年份：2024 发表杂志：Nature Communications

                            
                            Excess glucocorticoids inhibit murine bone turnover via modulating the immunometabolism of the skeletal microenvironment
                        

产品名称：Cpt1a-Flox

研究领域：罕见病;糖皮质激素相关骨骼疾病

发表年份：2024 发表杂志：JOURNAL OF CLINICAL INVESTIGATION

                            
                            The CDK4/6 inhibitor Palbociclib synergizes with ATRA to induce differentiation in AML
                        

产品名称：-

研究领域：

发表年份：2024 发表杂志：MOLECULAR CANCER THERAPEUTICS

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Fibrous periosteum repairs bone fracture and maintains the healed bone throughout mouse adulthood

Defective prelamin A processing promotes unconventional necroptosis driven by nuclear RIPK1

Nuclear microRNA-mediated transcriptional control determines adult microglial homeostasis and brain function

Restoring T and B cell generation in X-linked severe combined immunodeficiency mice through hematopoietic stem cells adenine base editing

The chemerin-CMKLR1 axis in keratinocytes impairs innate host defense against cutaneous Staphylococcus aureus infection

Restoring T and B cell generation in X-linked severe combined immunodeficiency mice through hematopoietic stem cells adenine base editing

HDAC6-dependent deacetylation of NGF dictates its ubiquitination and maintains primordial follicle dormancy

Serotonergic modulation of vigilance states in zebrafish and mice

Excess glucocorticoids inhibit murine bone turnover via modulating the immunometabolism of the skeletal microenvironment

The CDK4/6 inhibitor Palbociclib synergizes with ATRA to induce differentiation in AML

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