历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Cytosolic pH is a direct nexus in linking environmental cues with insulin processing and secretion in pancreatic β cells
                        

产品名称：Smad5-Flox;R26-GFP-Smad5_K;R26-GFP-Smad5_E1E2;R26-GFP-Smad5

研究领域：自身免疫及炎症;胰腺β细胞

发表年份：2024 发表杂志：Cell Metabolism

                            
                            ATG-101 is a tetravalent PD-L1×4-1BB bispecific antibody that stimulates anti-tumor immunity through PD-L1 blockade and PD-L1-directed 4-1BB activation
                        

产品名称：h4-1BB(2)

研究领域：肿瘤及肿瘤免疫;免疫检查点抑制剂(ICI)

发表年份：2024 发表杂志：CANCER RESEARCH

                            
                            Oncogenic KRAS induces arginine auxotrophy and confers a therapeutic vulnerability to SLC7A1 inhibition in non-small cell lung cancer
                        

产品名称：Kras-LSL-G12D

研究领域：肿瘤及肿瘤免疫;非小细胞肺癌

发表年份：2024 发表杂志：CANCER RESEARCH

Activation of GPR81 by lactate drives tumour-induced cachexia

产品名称：Kras-LSL-G12D/Trp53-Flox-R172H

研究领域：肿瘤及肿瘤免疫;癌症恶病质

发表年份：2024 发表杂志：Nature Metabolism

                            
                            Bacteria-mediated resistance of neutrophil extracellular traps to enzymatic degradation drives the formation of dental calculi
                        

产品名称：Padi4-KO

研究领域：其它;牙结石

发表年份：2024 发表杂志：Nature Biomedical Engineering

                            
                            Targeting ESE3/EHF With Nifurtimox Inhibits CXCR2+ Neutrophil Infiltration and Overcomes Pancreatic Cancer Resistance to Chemotherapy and Immunotherapy
                        

产品名称：Cd45.1(BALB/c)

研究领域：肿瘤及肿瘤免疫;胰腺癌

发表年份：2024 发表杂志：GASTROENTEROLOGY

                            
                            Histidine re-sensitizes pediatric acute lymphoblastic leukemia to 6-mercaptopurine through tetrahydrofolate consumption and SIRT5-mediated desuccinylation
                        

产品名称：-

研究领域：

发表年份：2024 发表杂志：Cell Death & Disease

                            
                            Microbial metabolite enhances immunotherapy efficacy by modulating T cell stemness in pan-cancer
                        

产品名称：Tcf7-KO

研究领域：肿瘤及肿瘤免疫;免疫检查点阻断(ICB)反应

发表年份：2024 发表杂志：CELL

Aspirin-Mediated Acetylation of SIRT1 Maintains Intestinal Immune Homeostasis

产品名称：BALB/c Nude

研究领域：自身免疫及炎症;阿司匹林

发表年份：2024 发表杂志：Advanced Science

                            
                            Elevated Kallistatin promotes the occurrence and progression of non-alcoholic fatty liver disease
                        

产品名称：CGI-58-Tg

研究领域：自身免疫及炎症;非酒精性脂肪性肝病(NAFLD

发表年份：2024 发表杂志：Signal Transduction and Targeted Therapy

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Cytosolic pH is a direct nexus in linking environmental cues with insulin processing and secretion in pancreatic β cells

ATG-101 is a tetravalent PD-L1×4-1BB bispecific antibody that stimulates anti-tumor immunity through PD-L1 blockade and PD-L1-directed 4-1BB activation

Oncogenic KRAS induces arginine auxotrophy and confers a therapeutic vulnerability to SLC7A1 inhibition in non-small cell lung cancer

Activation of GPR81 by lactate drives tumour-induced cachexia

Bacteria-mediated resistance of neutrophil extracellular traps to enzymatic degradation drives the formation of dental calculi

Targeting ESE3/EHF With Nifurtimox Inhibits CXCR2+ Neutrophil Infiltration and Overcomes Pancreatic Cancer Resistance to Chemotherapy and Immunotherapy

Histidine re-sensitizes pediatric acute lymphoblastic leukemia to 6-mercaptopurine through tetrahydrofolate consumption and SIRT5-mediated desuccinylation

Microbial metabolite enhances immunotherapy efficacy by modulating T cell stemness in pan-cancer

Aspirin-Mediated Acetylation of SIRT1 Maintains Intestinal Immune Homeostasis

Elevated Kallistatin promotes the occurrence and progression of non-alcoholic fatty liver disease

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