历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Ncf1 knockout in SMCs exacerbates angiotensin II-induced aortic aneurysm and dissection by activating the STING pathway
                        

产品名称：Ncf1-Flox

研究领域：肿瘤及肿瘤免疫;主动脉动脉瘤

发表年份：2024 发表杂志：CARDIOVASCULAR RESEARCH

                            
                            CXCL5 activates CXCR2 in nociceptive sensory neurons to drive joint pain and inflammation in experimental gouty arthritis
                        

产品名称：Ly6g-IRES-GFP

研究领域：自身免疫及炎症;痛风性关节炎

发表年份：2024 发表杂志：Nature Communications

Hepatic Klf10-Fh1 axis promotes exercise-mediated amelioration of NASH in mice

产品名称：Klf10-KO

研究领域：自身免疫及炎症;非酒精性脂肪性肝炎(NASH)

发表年份：2024 发表杂志：METABOLISM-CLINICAL AND EXPERIMENTAL

                            
                            Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
                        

产品名称：-

研究领域：

发表年份：2024 发表杂志：Cell Reports

                            
                            ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion
                        

产品名称：hCD3E;Itpripl1-KO

研究领域：肿瘤及肿瘤免疫;ITPRIPL1(或CD3L1， CD3ε配体1)

发表年份：2024 发表杂志：CELL

                            
                            An oncolytic virus delivering tumor-irrelevant bystander T cell epitopes induces anti-tumor immunity and potentiates cancer immunotherapy
                        

产品名称：MC38-OVA

研究领域：肿瘤及肿瘤免疫;TBYS细胞

发表年份：2024 发表杂志：Nature Cancer

                            
                            Human MHC Class II and Invariant Chain Knock-in Mice Mimic Rheumatoid Arthritis with Allele Restriction in Immune Response and Arthritis Association
                        

产品名称：COL2a1-K464R;COL2a1-D466E

研究领域：自身免疫及炎症;类风湿性关节炎

发表年份：2024 发表杂志：Advanced Science

                            
                            Myeloid Trem2 ameliorates the progression of metabolic dysfunction-associated steatotic liver disease by regulating macrophage pyroptosis and inflammation resolution
                        

产品名称：Trem2-Flox

研究领域：代谢心血管;代谢功能障碍相关脂肪变性肝病(MASLD)

发表年份：2024 发表杂志：METABOLISM-CLINICAL AND EXPERIMENTAL

                            
                            Spatiotemporal transcriptomic changes of human ovarian aging and the regulatory role of FOXP1
                        

产品名称：Foxp1-Flox;Cyp19a1-IRES-Cre

研究领域：其它;卵巢衰老

发表年份：2024 发表杂志：Nature Aging

                            
                            Small-molecule α-lipoic acid targets ELK1 to balance human neutrophil and erythrocyte differentiation
                        

产品名称：-

研究领域：

发表年份：2024 发表杂志：Stem Cell Research & Therapy

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Ncf1 knockout in SMCs exacerbates angiotensin II-induced aortic aneurysm and dissection by activating the STING pathway

CXCL5 activates CXCR2 in nociceptive sensory neurons to drive joint pain and inflammation in experimental gouty arthritis

Hepatic Klf10-Fh1 axis promotes exercise-mediated amelioration of NASH in mice

Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome

ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion

An oncolytic virus delivering tumor-irrelevant bystander T cell epitopes induces anti-tumor immunity and potentiates cancer immunotherapy

Human MHC Class II and Invariant Chain Knock-in Mice Mimic Rheumatoid Arthritis with Allele Restriction in Immune Response and Arthritis Association

Myeloid Trem2 ameliorates the progression of metabolic dysfunction-associated steatotic liver disease by regulating macrophage pyroptosis and inflammation resolution

Spatiotemporal transcriptomic changes of human ovarian aging and the regulatory role of FOXP1

Small-molecule α-lipoic acid targets ELK1 to balance human neutrophil and erythrocyte differentiation

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