历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Translocator protein facilitates neutrophil-mediated mucosal inflammation in inflammatory bowel diseases
                        

产品名称：C57BL/6

研究领域：IBD(炎症性肠病)

发表年份：2025 发表杂志：WORLD JOURNAL OF GASTROENTEROLOGY

                            
                            Targeting RelA/NLRP3/CCL3 axis mitigates microglia inflammatory response and promotes recovery after spinal cord injury
                        

产品名称：Nlrp3-Flox;Cx3cr1-CreERT2;R26-CAG-LSL-tdTomato

研究领域：神经

发表年份：2025 发表杂志：BRAIN BEHAVIOR AND IMMUNITY

                            
                            CircABCA1 promotes ccRCC by reprogramming cholesterol metabolism and facilitating M2 macrophage polarization through IGF2BP3-mediated stabilization of SCARB1 mRNA
                        

产品名称：M-NSG

研究领域：CAR-T治疗

发表年份：2025 发表杂志：Molecular Cancer

                            
                            Targeting CD37 promotes macrophage-dependent phagocytosis of multiple cancer cell types and facilitates tumor clearance in mice
                        

产品名称：Cd37-Flox

研究领域：肿瘤免疫

发表年份：2025 发表杂志：Nature Communications

                            
                            Dynein-Dependent Endo-Lysosomal Degradation Drives Lewy Body Disorders Accompanied by Aβ Pathology
                        

产品名称：5xFAD

研究领域：神经退行性疾病

发表年份：2025 发表杂志：Advanced Science

                            
                            Commensal Viruses Promote Intestinal Stem Cell Regeneration Following Radiation Damage by Inhibiting Hyperactivation of RIG-I and Notch Signals
                        

产品名称：Ddx58-Flox

研究领域：肠道病毒

发表年份：2025 发表杂志：Advanced Science

                            
                            Multiomic identification of senescent stem cell populations critical for osteoarthritis progression and therapy in subchondral bones
                        

产品名称：Ereg-KO

研究领域：自身免疫及炎症

发表年份：2025 发表杂志：Science Advances

                            
                            YOD1 regulates oxidative damage of dopamine neurons in Parkinson's disease by deubiquitinating PKM2
                        

产品名称：Yod1-KO;Yod1-Flox

研究领域：帕金森

发表年份：2025 发表杂志：Clinical and Translational Medicine

                            
                            ZBP1-sensed hypoxic stress triggers intrinsic necroptosis in hepatocytes, aggravating hepatic ischemia-reperfusion injury: an experimental study
                        

产品名称：Ripk3-Flox

研究领域：肝脏

发表年份：2025 发表杂志：International Journal of Surgery

                            
                            Modeling tumor relapse using proliferation tracing and ablation transgenic mouse
                        

产品名称：R26-CAG-LSL-RSR-tdTomato-2A-DTR

研究领域：肿瘤及肿瘤免疫

发表年份：2025 发表杂志：npj Breast Cancer

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Translocator protein facilitates neutrophil-mediated mucosal inflammation in inflammatory bowel diseases

Targeting RelA/NLRP3/CCL3 axis mitigates microglia inflammatory response and promotes recovery after spinal cord injury

CircABCA1 promotes ccRCC by reprogramming cholesterol metabolism and facilitating M2 macrophage polarization through IGF2BP3-mediated stabilization of SCARB1 mRNA

Targeting CD37 promotes macrophage-dependent phagocytosis of multiple cancer cell types and facilitates tumor clearance in mice

Dynein-Dependent Endo-Lysosomal Degradation Drives Lewy Body Disorders Accompanied by Aβ Pathology

Commensal Viruses Promote Intestinal Stem Cell Regeneration Following Radiation Damage by Inhibiting Hyperactivation of RIG-I and Notch Signals

Multiomic identification of senescent stem cell populations critical for osteoarthritis progression and therapy in subchondral bones

YOD1 regulates oxidative damage of dopamine neurons in Parkinson's disease by deubiquitinating PKM2

ZBP1-sensed hypoxic stress triggers intrinsic necroptosis in hepatocytes, aggravating hepatic ischemia-reperfusion injury: an experimental study

Modeling tumor relapse using proliferation tracing and ablation transgenic mouse

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