历年文献基因敲除小鼠_转基因小鼠定制

                            
                            OSK-mediated partial reprogramming induces cardiomyocyte dedifferentiation, overcomes cytokinesis barriers, and promotes post-MI endogenous cardiac regeneration
                        

产品名称：Myh6-Cre

研究领域：心脏再生；心肌细胞去分化；心肌梗死

发表年份：2026 发表杂志：JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiomyocytes FGFBP1 induction by STAT3 drives pathological cardiac remodeling

产品名称：Fgfbp1−KO

研究领域：心肌重塑；心衰

发表年份：2026 发表杂志：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

                            
                            ALDH2 deficiency increases susceptibility to acetaminophen-induced liver injury through gut microbiota dysbiosis and altered bile acid metabolism
                        

产品名称：Aldh2-KO

研究领域：对乙酰氨基酚肝损伤；肠道菌群失调；胆汁酸代谢

发表年份：2026 发表杂志：TOXICOLOGY AND APPLIED PHARMACOLOGY

                            
                            Prolactin drives the pathogenic amplification of atopic dermatitis by promoting CCL17 secretion through activation of the PI3K/AKT pathway
                        

产品名称：Prlr-Flox

研究领域：特应性皮炎；催乳素

发表年份：2026 发表杂志：FREE RADICAL BIOLOGY AND MEDICINE

                            
                            Mammary organoid-based depot for post-surgical chemotherapy and gland regeneration
                        

产品名称：M-NSG

研究领域：乳腺类器官；术后化疗；腺体再生；药物递送

发表年份：2026 发表杂志：Nature Biomedical Engineering

                            
                            Faecalibacterium prausnitzii enzyme reprograms PD-L1 trafficking and sensitizes colorectal cancer to immunotherapy in mice
                        

产品名称：BALB/c Nude; MC38

研究领域：结直肠癌；免疫治疗；PD-L1；普拉梭菌酶

发表年份：2026 发表杂志：Nature Microbiology

                            
                            SEC62 at mitochondria-associated membranes drives MASH progression by suppressing ATAD3B-mediated mitochondrial quality control
                        

产品名称：Rosa26-CAG-LNL-Cas9

研究领域：MASH；内质网应激；氧化应激

发表年份：2026 发表杂志：METABOLISM-CLINICAL AND EXPERIMENTAL

                            
                            A novel mRNA-based therapeutic vaccine elicits robust anti-tumor immunity against HPV-associated malignancies
                        

产品名称：M-NSG

研究领域：mRNA治疗性疫苗；HPV；肿瘤；抗肿瘤免疫

发表年份：2026 发表杂志：Frontiers in Immunology

                            
                            Dexmedetomidine attenuates Alzheimer’s pathogenesis by targeting the ROS-mediated XIAP-MDM2-p53 signaling axis
                        

产品名称：5×FAD

研究领域：阿尔茨海默病；认知障碍

发表年份：2026 发表杂志：Frontiers in Pharmacology

                            
                            8-Me-PIQ Expands Cord Blood CD34+ Hematopoietic Stem and Progenitor Cells via Metabolic Suppression and Inhibition of Ribosome Biogenesis
                        

产品名称：M-NSG

研究领域：造血干细胞；脐带血；代谢抑制；核糖体生物合成

发表年份：2026 发表杂志：Stem Cell Reviews and Reports

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OSK-mediated partial reprogramming induces cardiomyocyte dedifferentiation, overcomes cytokinesis barriers, and promotes post-MI endogenous cardiac regeneration

Cardiomyocytes FGFBP1 induction by STAT3 drives pathological cardiac remodeling

ALDH2 deficiency increases susceptibility to acetaminophen-induced liver injury through gut microbiota dysbiosis and altered bile acid metabolism

Prolactin drives the pathogenic amplification of atopic dermatitis by promoting CCL17 secretion through activation of the PI3K/AKT pathway

Mammary organoid-based depot for post-surgical chemotherapy and gland regeneration

Faecalibacterium prausnitzii enzyme reprograms PD-L1 trafficking and sensitizes colorectal cancer to immunotherapy in mice

SEC62 at mitochondria-associated membranes drives MASH progression by suppressing ATAD3B-mediated mitochondrial quality control

A novel mRNA-based therapeutic vaccine elicits robust anti-tumor immunity against HPV-associated malignancies

Dexmedetomidine attenuates Alzheimer’s pathogenesis by targeting the ROS-mediated XIAP-MDM2-p53 signaling axis

8-Me-PIQ Expands Cord Blood CD34+ Hematopoietic Stem and Progenitor Cells via Metabolic Suppression and Inhibition of Ribosome Biogenesis

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