历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Neurotoxicity, α-synuclein pathology, and mitochondrial dysfunction: A comparative study of different mouse models of Parkinson’s disease
                        

产品名称：Tfam-Flox

研究领域：帕金森

发表年份：2025 发表杂志：Neural Regeneration Research

                            
                            The deubiquitinase USP17LA negatively regulates T-cell activation and attenuates anti-tumor immunity
                        

产品名称：Usp17la-KO

研究领域：肿瘤免疫

发表年份：2025 发表杂志：EMBO REPORTS

                            
                            Endothelial Gasdermin D Induces Mitochondrial Damage and Activates the STING Pathway in Lipopolysaccharide-Accelerated Atherosclerosis
                        

产品名称：Gsdmd-Flox;Tie1-2A-Cre;APOE-KO

研究领域：动脉粥样硬化

发表年份：2025 发表杂志：ANTIOXIDANTS & REDOX SIGNALING

                            
                            Cholesterol 25-Hydroxylase Enhances Myeloid-Derived Suppressor Cell (MDSC) Immunosuppression via the Stimulator of Interferon Genes (STING)-Tank-Binding Kinase 1 (TBK1)-Receptor-Interacting Protein Kinase 3 (RIPK3) Pathway in Colorectal Cancer
                        

产品名称：Ch25h-Flox; Lyz2-Cre

研究领域：肿瘤及肿瘤免疫

发表年份：2025 发表杂志：MedComm

                            
                            Regular versus Irregular Exercise Differentially Modulates Hippocampal-Hepatic Acetylcholine Flux to Coordinate Fear Memory Extinction and Liver Inflammation
                        

产品名称：Ly6g-2A-CreERT2

研究领域：神经免疫代谢

发表年份：2025 发表杂志：Advanced Science

                            
                            An Engineered Probiotic Consortium Based on Quorum-Sensing for Colorectal Cancer Immunotherapy
                        

产品名称：hPD-1/hPD-L1;M-NSG

研究领域：大肠癌免疫治疗

发表年份：2025 发表杂志：Advanced Science

                            
                            A traditional herbal decoction regulates skeletal muscle satellite cell osteogenesis and myogenesis for repairing osteosarcopenic fractures via β-catenin
                        

产品名称：C57BL/6

研究领域：肿瘤及肿瘤免疫

发表年份：2025 发表杂志：Stem Cell Research & Therapy

                            
                            Empagliflozin Attenuates Diabetic Cardiomyopathy via Inhibiting Cardiomyocyte Ferroptosis Through the USP7/NRF2 Signaling Pathway
                        

产品名称：Nfe2l2-KO

研究领域：糖尿病心肌病

发表年份：2025 发表杂志：ANTIOXIDANTS & REDOX SIGNALING

                            
                            Cryo-EM structure of the full-length LGR4-RSPOs complex and a targeting nanobody for anti-obesity therapy
                        

产品名称：饲养繁育

研究领域：肥胖靶向治疗

发表年份：2025 发表杂志：Nature Communications

                            
                            Secondary Bile Acids Modified by Odoribacter Splanchnicus Alleviate Colitis by Suppressing Neutrophil Extracellular Trap Formation
                        

产品名称：Il10-KO;Padi4-KO;Nlrp3-KO

研究领域：肠道菌群

发表年份：2025 发表杂志：Advanced Science

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Neurotoxicity, α-synuclein pathology, and mitochondrial dysfunction: A comparative study of different mouse models of Parkinson’s disease

The deubiquitinase USP17LA negatively regulates T-cell activation and attenuates anti-tumor immunity

Endothelial Gasdermin D Induces Mitochondrial Damage and Activates the STING Pathway in Lipopolysaccharide-Accelerated Atherosclerosis

Cholesterol 25-Hydroxylase Enhances Myeloid-Derived Suppressor Cell (MDSC) Immunosuppression via the Stimulator of Interferon Genes (STING)-Tank-Binding Kinase 1 (TBK1)-Receptor-Interacting Protein Kinase 3 (RIPK3) Pathway in Colorectal Cancer

Regular versus Irregular Exercise Differentially Modulates Hippocampal-Hepatic Acetylcholine Flux to Coordinate Fear Memory Extinction and Liver Inflammation

An Engineered Probiotic Consortium Based on Quorum-Sensing for Colorectal Cancer Immunotherapy

A traditional herbal decoction regulates skeletal muscle satellite cell osteogenesis and myogenesis for repairing osteosarcopenic fractures via β-catenin

Empagliflozin Attenuates Diabetic Cardiomyopathy via Inhibiting Cardiomyocyte Ferroptosis Through the USP7/NRF2 Signaling Pathway

Cryo-EM structure of the full-length LGR4-RSPOs complex and a targeting nanobody for anti-obesity therapy

Secondary Bile Acids Modified by Odoribacter Splanchnicus Alleviate Colitis by Suppressing Neutrophil Extracellular Trap Formation

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