历年文献基因敲除小鼠_转基因小鼠定制

                            
                            PERK Maintains Hematopoietic Stem Cell Pool Integrity under Endoplasmic Reticulum Stress by Promoting Proliferation
                        

产品名称：Eif2ak3-flox-K618A

研究领域：造血干细胞

发表年份：2025 发表杂志：BLOOD

                            
                            Emodin Inhibits NLRP3 Inflammasome Activation and Protects Against Sepsis via Promoting FUNDC1-Mediated Mitophagy
                        

产品名称：Nlrp3-KO

研究领域：自身免疫及炎症

发表年份：2025 发表杂志：International Journal of Biological Sciences

                            
                            CBX5 loss drives Pl3Kδ inhibitor resistance in mantle cell lymphoma and propolis restores sensitivity by inducing CBX5-mediated ferroptosis
                        

产品名称：M-NSG

研究领域：肿瘤及肿瘤免疫

发表年份：2025 发表杂志：PHYTOMEDICINE

                            
                            Ferroptosis-activating metabolite acrolein antagonizes necroptosis and anti-cancer therapeutics
                        

产品名称：BALB/c; BALB/c Nude

研究领域：肿瘤免疫

发表年份：2025 发表杂志：Nature Communications

Machine-learning-assisted universal protein activation in living mice

产品名称：MC38-hPD-L1

研究领域：蛋白质调控

发表年份：2025 发表杂志：CELL

                            
                            Psychological stress-induced ALKBH5 deficiency promotes tumour innervation and pancreatic cancer via extracellular vesicle transfer of RNA
                        

产品名称：KPC

研究领域：肿瘤及肿瘤免疫

发表年份：2025 发表杂志：NATURE CELL BIOLOGY

                            
                            KLK8/HGF/Met signaling pathway mediates diabetes-associated hippocampal neuroinflammation in male mice
                        

产品名称：Klk8-KO

研究领域：神经炎症

发表年份：2025 发表杂志：Theranostics

                            
                            FOXK2 in skeletal muscle development: a new pathogenic gene for congenital myopathy with ptosis
                        

产品名称：Foxk2-Flox;Foxk2-KO

研究领域：罕见病

发表年份：2025 发表杂志：EMBO Molecular Medicine

                            
                            Neoantigen enriched biomimetic nanovaccine for personalized cancer immunotherapy
                        

产品名称：Batf3-KO; M-NSG

研究领域：肿瘤免疫

发表年份：2025 发表杂志：Nature Communications

                            
                            IFI204 in microglia mediates traumatic brain injury-induced mitochondrial dysfunction and pyroptosis via SENP7 interaction
                        

产品名称：Ifi204-Flox;Cx3cr1-CreERT2

研究领域：神经科学

发表年份：2025 发表杂志：CELL BIOLOGY AND TOXICOLOGY

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PERK Maintains Hematopoietic Stem Cell Pool Integrity under Endoplasmic Reticulum Stress by Promoting Proliferation

Emodin Inhibits NLRP3 Inflammasome Activation and Protects Against Sepsis via Promoting FUNDC1-Mediated Mitophagy

CBX5 loss drives Pl3Kδ inhibitor resistance in mantle cell lymphoma and propolis restores sensitivity by inducing CBX5-mediated ferroptosis

Ferroptosis-activating metabolite acrolein antagonizes necroptosis and anti-cancer therapeutics

Machine-learning-assisted universal protein activation in living mice

Psychological stress-induced ALKBH5 deficiency promotes tumour innervation and pancreatic cancer via extracellular vesicle transfer of RNA

KLK8/HGF/Met signaling pathway mediates diabetes-associated hippocampal neuroinflammation in male mice

FOXK2 in skeletal muscle development: a new pathogenic gene for congenital myopathy with ptosis

Neoantigen enriched biomimetic nanovaccine for personalized cancer immunotherapy

IFI204 in microglia mediates traumatic brain injury-induced mitochondrial dysfunction and pyroptosis via SENP7 interaction

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