历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Loss of SETD2 aggravates colorectal cancer progression caused by SMAD4 deletion through the RAS/ERK signalling pathway
                        

产品名称：Setd2-Flox(2)

研究领域：肿瘤及肿瘤免疫;结直肠癌(CRC)

发表年份：2023 发表杂志：Clinical and Translational Medicine

                            
                            Balance of Gata3 and Ramp2 in hepatocytes regulates hepatic vascular reconstitution in postoperative liver regeneration
                        

产品名称：R26-CAG-LNL-Cas9-IRES-Luc

研究领域：肝脏

发表年份：2023-11-13 发表杂志：JOURNAL OF HEPATOLOGY

                            
                            RNA m6A methylation modulates airway inflammation in allergic asthma via PTX3- dependent macrophage homeostasis
                        

产品名称：Mettl3-Flox

研究领域：过敏性哮喘

发表年份：2023-11-13 发表杂志：nature communications

                            
                            RNA m6A methylation modulates airway inflammation in allergic asthma via PTX3-dependent macrophage homeostasis
                        

产品名称：Mettl3-Flox

研究领域：自身免疫及炎症;过敏性哮喘

发表年份：2023 发表杂志：Nature Communications

                            
                            The lysine methyltransferase SMYD2 facilitates neointimal hyperplasia by regulating the HDAC3–SRF axis
                        

产品名称：Tagln-CreERT2

研究领域：代谢心血管;冠心病

发表年份：2023 发表杂志：Acta Pharmaceutica Sinica B

                            
                            SETD2 deficiency promotes renal fibrosis through the TGF-β/Smad signalling pathway in the absence of VHL
                        

产品名称：Setd2-Flox(2)

研究领域：自身免疫及炎症;肾纤维化

发表年份：2023 发表杂志：Clinical and Translational Medicine

                            
                            TROP2-directed nanobody-drug conjugate elicited potent antitumor effect in pancreatic cancer
                        

产品名称：M-NSG

研究领域：肿瘤及肿瘤免疫;胰腺癌

发表年份：2023 发表杂志：JOURNAL OF NANOBIOTECHNOLOGY

                            
                            Tumor cell-released kynurenine biases MEP differentiation into megakaryocytes in individuals with cancer by activating AhR–RUNX1
                        

产品名称：pPrm1-tdTomato-Tg

研究领域：代谢心血管

发表年份：2023 发表杂志：NATURE IMMUNOLOGY

                            
                            Activated Drp1 Initiates the Formation of Endoplasmic Reticulum-Mitochondrial Contacts via Shrm4-Mediated Actin Bundling
                        

产品名称：Dnm1l-KO

研究领域：自身免疫及炎症;细胞质Drp1

发表年份：2023 发表杂志：Advanced Science

                            
                            IRE1α protects against osteoarthritis by regulating progranulin-dependent XBP1 splicing and collagen homeostasis
                        

产品名称：Ern1-Flox

研究领域：自身免疫及炎症;骨关节炎(OA)

发表年份：2023 发表杂志：EXPERIMENTAL AND MOLECULAR MEDICINE

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Loss of SETD2 aggravates colorectal cancer progression caused by SMAD4 deletion through the RAS/ERK signalling pathway

Balance of Gata3 and Ramp2 in hepatocytes regulates hepatic vascular reconstitution in postoperative liver regeneration

RNA m6A methylation modulates airway inflammation in allergic asthma via PTX3- dependent macrophage homeostasis

RNA m6A methylation modulates airway inflammation in allergic asthma via PTX3-dependent macrophage homeostasis

The lysine methyltransferase SMYD2 facilitates neointimal hyperplasia by regulating the HDAC3–SRF axis

SETD2 deficiency promotes renal fibrosis through the TGF-β/Smad signalling pathway in the absence of VHL

TROP2-directed nanobody-drug conjugate elicited potent antitumor effect in pancreatic cancer

Tumor cell-released kynurenine biases MEP differentiation into megakaryocytes in individuals with cancer by activating AhR–RUNX1

Activated Drp1 Initiates the Formation of Endoplasmic Reticulum-Mitochondrial Contacts via Shrm4-Mediated Actin Bundling

IRE1α protects against osteoarthritis by regulating progranulin-dependent XBP1 splicing and collagen homeostasis

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