历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Cyclophilin J Reprograms Tumor-associated Macrophages to Exert an Anti-tumor Effect in Liver Cancer
                        

产品名称：Ppil3-KO

研究领域：肿瘤及肿瘤免疫

发表年份：2025 发表杂志：International Journal of Biological Sciences

                            
                            7-α-O-Methylmorroniside ameliorated brain injury in 5×FAD mice by regulating the gut microbiome and NMDAR2B
                        

产品名称：5×FAD

研究领域：阿尔兹海默

发表年份：2025 发表杂志：Frontiers in Pharmacology

                            
                            SRSF10 regulates oligodendrocyte differentiation during mouse central nervous system development by modulating pre-mRNA splicing
                        

产品名称：Srsf12-Flox

研究领域：神经发育

发表年份：2025 发表杂志：NUCLEIC ACIDS RESEARCH

                            
                            Astragaloside IV inhibits the growth of obesity-associated triple-negative breast cancer by activating FOXA1 transcription factor to regulate GAL3ST1-GalCer signaling and remodel sphingolipid metabolism
                        

产品名称：SCID

研究领域：肿瘤及肿瘤免疫

发表年份：2025 发表杂志：PHYTOMEDICINE

                            
                            Bacteroides fragilis promotes chemoresistance in colorectal cancer, and its elimination by phage VA7 restores chemosensitivity
                        

产品名称：Notch1-KO; Notch1-Flox

研究领域：肿瘤及肿瘤免疫

发表年份：2025 发表杂志：Cell Host & Microbe

                            
                            Exosome-derived SLC12A2-DT promotes macrophage M2 polarization-mediated hepatocellular carcinoma progression
                        

产品名称：BALB/c Nude

研究领域：肝癌

发表年份：2025 发表杂志：INTERNATIONAL IMMUNOPHARMACOLOGY

                            
                            Overexpression of thioredoxin 1 contributes to neuroprotection through ATM activation and pentose phosphate pathway modulation after traumatic brain injury
                        

产品名称：C57BL/6

研究领域：神经

发表年份：2025 发表杂志：EXPERIMENTAL NEUROLOGY

                            
                            Macrophage extracellular traps as key mediators of scleral remodeling in myopia induced by hypoxia and activated platelets
                        

产品名称：Padi4-KO

研究领域：肿瘤及肿瘤免疫

发表年份：2025 发表杂志：Cell Reports

                            
                            Dietary advanced glycation end-products promote food allergy by disrupting intestinal barrier and enhancing Th2 immunity
                        

产品名称：Ager-KO Tlr4-KO

研究领域：自身免疫及炎症

发表年份：2025 发表杂志：Nature Communications

                            
                            Arginase 1 drives mitochondrial cristae remodeling and PANoptosis in ischemia/hypoxia-induced vascular dysfunction
                        

产品名称：Arg1-flox

研究领域：血管

发表年份：2025 发表杂志：Signal Transduction and Targeted Therapy

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Cyclophilin J Reprograms Tumor-associated Macrophages to Exert an Anti-tumor Effect in Liver Cancer

7-α-O-Methylmorroniside ameliorated brain injury in 5×FAD mice by regulating the gut microbiome and NMDAR2B

SRSF10 regulates oligodendrocyte differentiation during mouse central nervous system development by modulating pre-mRNA splicing

Astragaloside IV inhibits the growth of obesity-associated triple-negative breast cancer by activating FOXA1 transcription factor to regulate GAL3ST1-GalCer signaling and remodel sphingolipid metabolism

Bacteroides fragilis promotes chemoresistance in colorectal cancer, and its elimination by phage VA7 restores chemosensitivity

Exosome-derived SLC12A2-DT promotes macrophage M2 polarization-mediated hepatocellular carcinoma progression

Overexpression of thioredoxin 1 contributes to neuroprotection through ATM activation and pentose phosphate pathway modulation after traumatic brain injury

Macrophage extracellular traps as key mediators of scleral remodeling in myopia induced by hypoxia and activated platelets

Dietary advanced glycation end-products promote food allergy by disrupting intestinal barrier and enhancing Th2 immunity

Arginase 1 drives mitochondrial cristae remodeling and PANoptosis in ischemia/hypoxia-induced vascular dysfunction

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