历年文献基因敲除小鼠_转基因小鼠定制

                            
                            JCAD deficiency attenuates activation of hepatic stellate cells and cholestatic fibrosis
                        

产品名称：Jcad-flox

研究领域：自身免疫及炎症;胆汁淤积性肝病

发表年份：2024 发表杂志：Clinical and Molecular Hepatology

                            
                            TREM2 macrophage promotes cardiac repair in myocardial infarction by reprogramming metabolism via SLC25A53
                        

产品名称：Trem2-Flox

研究领域：自身免疫及炎症;心肌梗死(MI)

发表年份：2024 发表杂志：CELL DEATH AND DIFFERENTIATION

                            
                            LncRNA ZNF674-AS1 drives cell growth and inhibits cisplatin-induced pyroptosis via up-regulating CA9 in neuroblastoma
                        

产品名称：-

研究领域：

发表年份：2024 发表杂志：Cell Death & Disease

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

产品名称：hACE2

研究领域：自身免疫及炎症;SARS-CoV-2核衣壳蛋白(SARS2-NP)

发表年份：2024 发表杂志：Nature Communications

                            
                            Targeting IL-17A enhances imatinib efficacy in Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia
                        

产品名称：Il17a-KO

研究领域：罕见病;白血病

发表年份：2024 发表杂志：Nature Communications

                            
                            Follicle stimulating hormone controls granulosa cell glutamine synthesis to regulate ovulation
                        

产品名称：Esr1-KO

研究领域：自身免疫及炎症;多囊卵巢综合征(PCOS)

发表年份：2024 发表杂志：Protein & Cell

                            
                            Salvianolic acid B attenuates liver fibrosis by targeting Ecm1 and inhibiting hepatocyte ferroptosis
                        

产品名称：Ecm1-Flox;Ecm1-KO

研究领域：自身免疫及炎症;肝纤维化

发表年份：2024 发表杂志：Redox Biology

                            
                            Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation
                        

产品名称：Sirt3-KO;CAG-LSL-hAARS2

研究领域：自身免疫及炎症;氧化磷酸化(OXPHOS)

发表年份：2024 发表杂志：CELL RESEARCH

                            
                            Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
                        

产品名称：M-NSG

研究领域：肿瘤及肿瘤免疫;嵌合抗原受体(CAR) T细胞治疗

发表年份：2024 发表杂志：Cell Metabolism

                            
                            Pharmacological inhibition of MYC to mitigate  chemoresistance in preclinical models of squamous cell  carcinoma
                        

产品名称：-

研究领域：

发表年份：2024-01-01 发表杂志：Theranostics

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JCAD deficiency attenuates activation of hepatic stellate cells and cholestatic fibrosis

TREM2 macrophage promotes cardiac repair in myocardial infarction by reprogramming metabolism via SLC25A53

LncRNA ZNF674-AS1 drives cell growth and inhibits cisplatin-induced pyroptosis via up-regulating CA9 in neuroblastoma

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Targeting IL-17A enhances imatinib efficacy in Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia

Follicle stimulating hormone controls granulosa cell glutamine synthesis to regulate ovulation

Salvianolic acid B attenuates liver fibrosis by targeting Ecm1 and inhibiting hepatocyte ferroptosis

Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation

Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation

Pharmacological inhibition of MYC to mitigate chemoresistance in preclinical models of squamous cell carcinoma

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