历年文献基因敲除小鼠_转基因小鼠定制

                            
                            New mechanistic understanding of FXR agonist Vonafexor: inducing sublethal damage of HBV-positive liver cancer cells via promoting anti-tumor immunity
                        

产品名称：Hu-HSC

研究领域：肿瘤免疫

发表年份：2025 发表杂志：BRITISH JOURNAL OF CANCER

                            
                            Optimization of a Novel 2 + 2 BCMA × CD3 Bispecific Antibody for Minimized Cytokine Release and Potent Efficacy
                        

产品名称：M-NSG

研究领域：肿瘤免疫

发表年份：2025 发表杂志：MOLECULAR CANCER THERAPEUTICS

                            
                            CD131 contributes to ulcerative colitis pathogenesis by promoting macrophage infiltration
                        

产品名称：Csf2rb-KO

研究领域：肠道炎症

发表年份：2025 发表杂志：eLife

Myeloid PD-1 Regulates Astrocyte Development and Leads to Active Behaviours

产品名称：Pd-1-Flox

研究领域：神经科学

发表年份：2025 发表杂志：CELL PROLIFERATION

                            
                            Semaphorin 3A protects against thoracic aortic aneurysm dissection by suppressing aortic angiogenesis
                        

产品名称：Sema3a-Flox，R26-TH-LSL-Sema3a-IRES-GFP

研究领域：代谢心血管

发表年份：2025 发表杂志：ANGIOGENESIS

Piezo1 disrupts blood–brain barrier via CaMKII/Nrf2 in ischemic stroke

产品名称：Piezo1-Flox

研究领域：神经科学

发表年份：2025 发表杂志：CELLULAR AND MOLECULAR LIFE SCIENCES

                            
                            Depression exacerbates AD pathology through lactate-dependent activation of microglial Kv1.3 to promote Aβ-containing exosome spreading
                        

产品名称：TMEM119-Cre

研究领域：神经

发表年份：2025 发表杂志：Journal of Neuroinflammation

                            
                            N-Lactoyl-Phenylalanine modulates lipid metabolism in microglia/macrophage via the AMPK-PGC1α-PPARγ pathway to promote recovery in mice with spinal cord injury
                        

产品名称：R26-CAG-LSL-tdTomato

研究领域：神经

发表年份：2025 发表杂志：Journal of Neuroinflammation

                            
                            Cingulin is an RNA-binding protein promoting pancreatic cancer through enhancing importin 7-mediated phospho-ERK nuclear translocation
                        

产品名称：Pdx1-2A-Cre

研究领域：肿瘤及肿瘤免疫

发表年份：2025 发表杂志：Cell Reports

                            
                            Gut bacteriophages induce specific-reprogramming of macrophages to generate a protective innate immunity response to lipopolysaccharide exposure
                        

产品名称：Il1b-Luc-2A-EGFP

研究领域：自身免疫及炎症

发表年份：2025 发表杂志：Gut Microbes

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New mechanistic understanding of FXR agonist Vonafexor: inducing sublethal damage of HBV-positive liver cancer cells via promoting anti-tumor immunity

Optimization of a Novel 2 + 2 BCMA × CD3 Bispecific Antibody for Minimized Cytokine Release and Potent Efficacy

CD131 contributes to ulcerative colitis pathogenesis by promoting macrophage infiltration

Myeloid PD-1 Regulates Astrocyte Development and Leads to Active Behaviours

Semaphorin 3A protects against thoracic aortic aneurysm dissection by suppressing aortic angiogenesis

Piezo1 disrupts blood–brain barrier via CaMKII/Nrf2 in ischemic stroke

Depression exacerbates AD pathology through lactate-dependent activation of microglial Kv1.3 to promote Aβ-containing exosome spreading

N-Lactoyl-Phenylalanine modulates lipid metabolism in microglia/macrophage via the AMPK-PGC1α-PPARγ pathway to promote recovery in mice with spinal cord injury

Cingulin is an RNA-binding protein promoting pancreatic cancer through enhancing importin 7-mediated phospho-ERK nuclear translocation

Gut bacteriophages induce specific-reprogramming of macrophages to generate a protective innate immunity response to lipopolysaccharide exposure

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