历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Cisplatin-induced Pyroptosis Enhances the Efficacy of PD-L1 Inhibitor in Small-Cell Lung Cancer via GSDME/IL12/CD4Tem Axis
                        

产品名称：-

研究领域：

发表年份：2024 发表杂志：International Journal of Biological Sciences

                            
                            Targeting cancer-associated fibroblast autophagy renders pancreatic cancer eradicable with immunochemotherapy by inhibiting adaptive immune resistance
                        

产品名称：Acta2-CreERT2

研究领域：肿瘤及肿瘤免疫;胰腺导管腺癌(PDAC)

发表年份：2024 发表杂志：Autophagy

                            
                            Pharmacological inhibition of MYC to mitigate chemoresistance in preclinical models of squamous cell carcinoma
                        

产品名称：Myc-Flox;Krt14-CreERT2

研究领域：肿瘤及肿瘤免疫;晚期头颈部鳞状细胞癌(HNSCC)

发表年份：2024 发表杂志：Theranostics

                            
                            Vitamin D binding protein (VDBP) hijacks twist1 to inhibit vasculogenic mimicry in hepatocellular carcinoma
                        

产品名称：Gc-Flox

研究领域：肿瘤及肿瘤免疫;肝细胞癌(HCC)

发表年份：2024 发表杂志：Theranostics

                            
                            Annotation of CD8+ T-cell function via ICAM-1 imaging identifies FAK inhibition as an adjuvant to augment the antitumor immunity of radiotherapy
                        

产品名称：Icam1-KO

研究领域：肿瘤及肿瘤免疫;放射治疗(RT)

发表年份：2024 发表杂志：Theranostics

                            
                            RCAd-LTH-shPD-L1, a double-gene recombinant oncolytic adenovirus with enhanced antitumor immunity, increases lymphocyte infiltration and reshapes the tumor microenvironment
                        

产品名称：M-NSG

研究领域：肿瘤及肿瘤免疫;RCAd-LTH-shPD-L1

发表年份：2024 发表杂志：Journal for ImmunoTherapy of Cancer

                            
                            Renal macrophages monitor and remove particles from urine to prevent tubule obstruction
                        

产品名称：Ccr2-KO

研究领域：代谢心血管;肾结石

发表年份：2023 发表杂志：IMMUNITY

                            
                            Excessive nucleic acid R-loops induce mitochondria-dependent epithelial cell necroptosis and drive spontaneous intestinal inflammation
                        

产品名称：Il10-KO;Zbp1-KO

研究领域：自身免疫及炎症;炎症性肠病(IBD)

发表年份：2023 发表杂志：PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

                            
                            TMEM135 maintains the equilibrium of osteogenesis and adipogenesis by regulating mitochondrial dynamics
                        

产品名称：Tmem135-KO

研究领域：骨质疏松症

发表年份：2023-12-26 发表杂志：Metabolism: Clinical and Experimental

                            
                            CAR-Aptamers Enable Traceless Enrichment and Monitoring of CAR-Positive Cells and Overcome Tumor Immune Escape
                        

产品名称：M-NSG

研究领域：自身免疫及炎症;car特异性结合适体(CAR-ap)

发表年份：2023 发表杂志：Advanced Science

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Cisplatin-induced Pyroptosis Enhances the Efficacy of PD-L1 Inhibitor in Small-Cell Lung Cancer via GSDME/IL12/CD4Tem Axis

Targeting cancer-associated fibroblast autophagy renders pancreatic cancer eradicable with immunochemotherapy by inhibiting adaptive immune resistance

Pharmacological inhibition of MYC to mitigate chemoresistance in preclinical models of squamous cell carcinoma

Vitamin D binding protein (VDBP) hijacks twist1 to inhibit vasculogenic mimicry in hepatocellular carcinoma

Annotation of CD8+ T-cell function via ICAM-1 imaging identifies FAK inhibition as an adjuvant to augment the antitumor immunity of radiotherapy

RCAd-LTH-shPD-L1, a double-gene recombinant oncolytic adenovirus with enhanced antitumor immunity, increases lymphocyte infiltration and reshapes the tumor microenvironment

Renal macrophages monitor and remove particles from urine to prevent tubule obstruction

Excessive nucleic acid R-loops induce mitochondria-dependent epithelial cell necroptosis and drive spontaneous intestinal inflammation

TMEM135 maintains the equilibrium of osteogenesis and adipogenesis by regulating mitochondrial dynamics

CAR-Aptamers Enable Traceless Enrichment and Monitoring of CAR-Positive Cells and Overcome Tumor Immune Escape

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