历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Th17 cells secrete TWEAK to trigger epithelial-mesenchymal transition and promote colorectal cancer liver metastasis
                        

产品名称：Il17a-KO;Tnfsf12-KO

研究领域：肿瘤及肿瘤免疫;结直肠癌

发表年份：2024 发表杂志：CANCER RESEARCH

                            
                            Extending dual-targeting upper-limit in liposomal delivery of lithospermic acid B for Alzheimer's mitochondrial revitalization
                        

产品名称：C57BL/6(老龄鼠)

研究领域：神经;阿尔茨海默病(AD)

发表年份：2024 发表杂志：JOURNAL OF CONTROLLED RELEASE

                            
                            miR-590-3p Overexpression Improves the Efficacy of hiPSC-CMs for Myocardial Repair
                        

产品名称：-

研究领域：

发表年份：2024 发表杂志：JACC-Basic to Translational Science

                            
                            Isolation and characterization of a pangolin-borne HKU4-related coronavirus that potentially infects human-DPP4-transgenic mice
                        

产品名称：hDPP4

研究领域：其它;hku4相关冠状病毒

发表年份：2024 发表杂志：Nature Communications

                            
                            Integrated multi-omics reveal gut microbiota-mediated bile acid metabolism alteration regulating immunotherapy responses to anti-α4β7-integrin in Crohn’s disease
                        

产品名称：M-NSG

研究领域：自身免疫及炎症;克罗恩病

发表年份：2024 发表杂志：Gut Microbes

                            
                            Dehydrocostus lactone alleviates irinotecan-induced intestinal mucositis by blocking TLR4/MD2 complex formation
                        

产品名称：-

研究领域：

发表年份：2024 发表杂志：PHYTOMEDICINE

                            
                            Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells
                        

产品名称：Rag2-KO;Tcrα-KO

研究领域：肿瘤及肿瘤免疫;FGF21

发表年份：2024 发表杂志：Cell Metabolism

                            
                            Phosphorylation of human glioma-associated oncogene 1 on Ser937 regulates Sonic Hedgehog signaling in medulloblastoma
                        

产品名称：Gli1-S941E;Gli1-S941A

研究领域：肿瘤及肿瘤免疫;SHH依赖性成神经管细胞瘤(MBSHH)和基底细胞癌(BCC)

发表年份：2024 发表杂志：Nature Communications

                            
                            Microglial Ffar4 deficiency promotes cognitive impairment in the context of metabolic syndrome
                        

产品名称：Ffar4-Flox

研究领域：代谢心血管;代谢综合征(MetS)

发表年份：2024 发表杂志：Science Advances

                            
                            Bacterial protoplast-derived nanovesicles carrying CRISPR-Cas9 tools re-educate tumor-associated macrophages for enhanced cancer immunotherapy
                        

产品名称：Tlr9-KO

研究领域：其它;CRISPR-Cas9系统

发表年份：2024 发表杂志：Nature Communications

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Th17 cells secrete TWEAK to trigger epithelial-mesenchymal transition and promote colorectal cancer liver metastasis

Extending dual-targeting upper-limit in liposomal delivery of lithospermic acid B for Alzheimer's mitochondrial revitalization

miR-590-3p Overexpression Improves the Efficacy of hiPSC-CMs for Myocardial Repair

Isolation and characterization of a pangolin-borne HKU4-related coronavirus that potentially infects human-DPP4-transgenic mice

Integrated multi-omics reveal gut microbiota-mediated bile acid metabolism alteration regulating immunotherapy responses to anti-α4β7-integrin in Crohn’s disease

Dehydrocostus lactone alleviates irinotecan-induced intestinal mucositis by blocking TLR4/MD2 complex formation

Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells

Phosphorylation of human glioma-associated oncogene 1 on Ser937 regulates Sonic Hedgehog signaling in medulloblastoma

Microglial Ffar4 deficiency promotes cognitive impairment in the context of metabolic syndrome

Bacterial protoplast-derived nanovesicles carrying CRISPR-Cas9 tools re-educate tumor-associated macrophages for enhanced cancer immunotherapy

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