历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Trifluridine/Tipiracil Exhibits Potent Antitumor Activity in Triple-Negative Breast Cancer by Targeting SKP2 and Inducing Cell Cycle Arrest and Apoptosis
                        

产品名称：NOD-SCID

研究领域：三阴性乳腺癌

发表年份：2025 发表杂志：Current Pharmaceutical Analysis

                            
                            YTHDF1 targets the chemotherapy response by suppressing NOTCH1-induced stemness in colorectal cancer
                        

产品名称：Rosa26-LSL-Ythdf1;Ythdf1-flox

研究领域：结直肠癌;肿瘤

发表年份：2025 发表杂志：Signal Transduction and Targeted Therapy

                            
                            Hepatocyte-specific partial cellular reprogramming via selective OSK mRNA lipid nanoparticle attenuates liver fibrosis
                        

产品名称：R26-CAG-LSL-Luc-tdTomato

研究领域：肝纤维化;代谢;mRNA递送

发表年份：2025 发表杂志：JOURNAL OF CONTROLLED RELEASE

                            
                            HNRNPH2 variant linked to intellectual disability disrupts myelination by impairing oligodendrocyte differentiation
                        

产品名称：Hnrnph2-P213L

研究领域：智力障碍;神经发育

发表年份：2025 发表杂志：Journal of Genetics and Genomics

                            
                            Propofol addiction drives neuronal senescence and cognitive decline via autophagy-mediated ADAR1/SIRT1 disruption
                        

产品名称：Cdkn2a-Flox(p16-Flox);Atg7-Flox

研究领域：神经毒性综合征;成瘾

发表年份：2025 发表杂志：Communications Biology

Tracing the origin of myofibroblasts in kidney fibrosis

产品名称：Hnf4a-2A-CreERT2;Cdh1-CreERT2

研究领域：肾纤维化;慢性肾病;炎症

发表年份：2025 发表杂志：Nature Communications

                            
                            The LRRK2 P1446L mutation triggers dopaminergic neurodegeneration via DAPK1-mediated microglial neuroinflammation and neuronal apoptosis
                        

产品名称：LRRK2-P1446L

研究领域：帕金森病;神经炎症;小胶质细胞

发表年份：2025 发表杂志：npj Parkinsons Disease

                            
                            Coke Oven Emission Exposure Triggers Malignant Transformation of Lung Epithelial Cells by SFTA1P-Dependent Alteration of Acetyl-CoA Metabolism
                        

产品名称：M-NSG

研究领域：肺癌;乙酰辅酶A代谢

发表年份：2025 发表杂志：Environment & Health

                            
                            Integrating global burden of disease analysis and single-cell omics identifies ANTXR2 as a potential diagnostic biomarker for AML in China
                        

产品名称：C57BL/6

研究领域：急性骨髓性白血病

发表年份：2025 发表杂志：INTERNATIONAL IMMUNOPHARMACOLOGY

                            
                            The SEMA7AN559Y mutation facilitates the development of metabolic dysfunction-associated steatotic liver disease by inducing ROS/NLRP3-mediated hepatic cell pyroptosis
                        

产品名称：Sema7-N557Y

研究领域：代谢功能障碍相关脂肪肝炎;代谢

发表年份：2025 发表杂志：METABOLISM-CLINICAL AND EXPERIMENTAL

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Trifluridine/Tipiracil Exhibits Potent Antitumor Activity in Triple-Negative Breast Cancer by Targeting SKP2 and Inducing Cell Cycle Arrest and Apoptosis

YTHDF1 targets the chemotherapy response by suppressing NOTCH1-induced stemness in colorectal cancer

Hepatocyte-specific partial cellular reprogramming via selective OSK mRNA lipid nanoparticle attenuates liver fibrosis

HNRNPH2 variant linked to intellectual disability disrupts myelination by impairing oligodendrocyte differentiation

Propofol addiction drives neuronal senescence and cognitive decline via autophagy-mediated ADAR1/SIRT1 disruption

Tracing the origin of myofibroblasts in kidney fibrosis

The LRRK2 P1446L mutation triggers dopaminergic neurodegeneration via DAPK1-mediated microglial neuroinflammation and neuronal apoptosis

Coke Oven Emission Exposure Triggers Malignant Transformation of Lung Epithelial Cells by SFTA1P-Dependent Alteration of Acetyl-CoA Metabolism

Integrating global burden of disease analysis and single-cell omics identifies ANTXR2 as a potential diagnostic biomarker for AML in China

The SEMA7AN559Y mutation facilitates the development of metabolic dysfunction-associated steatotic liver disease by inducing ROS/NLRP3-mediated hepatic cell pyroptosis

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