历年文献基因敲除小鼠_转基因小鼠定制

                            
                            V2C MXene Nanozyme Attenuates Sepsis-Induced Gut Injury via Paneth Cell Death and ER Stress Regulation
                        

产品名称：Atf6-Flox

研究领域：脓毒症肠损伤; 潘氏细胞死亡; 内质网应激

发表年份：2026 发表杂志：Advanced Healthcare Materials

                            
                            Loss of p53 exacerbates autoimmunity by reprogramming propionyl-CoA metabolism and histone modifications in Treg cells
                        

产品名称：Aldh6a1-Flox

研究领域：自身免疫; Treg细胞; p53缺失; 丙酰辅酶A代谢; 组蛋白修饰

发表年份：2026 发表杂志：Cell Reports

                            
                            Renal Tubule-Specific Deletion of Nephrocystin 3 (Nphp3) Causes Infantile Nephronophthisis-like Phenotypes in Mice
                        

产品名称：Nphp3-Flox/Cdh16-Cre; Nphp3-Flox

研究领域：肾消耗病; 纤毛病; 肾小管特异性敲除

发表年份：2026 发表杂志：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

                            
                            Mrgprb4-Lineage Neurons Participate in the Intervention of TENS Effects on Chronic Pain and Anxiety-like Symptoms in an Inflammatory Pain Mouse Model
                        

产品名称：Mrgprb4-mtdTomato-2A-NLSCre

研究领域：慢性疼痛; 经皮电刺激; 焦虑样行为

发表年份：2026 发表杂志：Biomedicines

                            
                            Pyruvate metabolism enzyme Dlat induces mitochondria protein hyperacetylation to limit fatty acid oxidation in the HFpEF heart
                        

产品名称：C57BL/6

研究领域：HFpEF; 丙酮酸代谢; 线粒体蛋白乙酰化; 脂肪酸氧化

发表年份：2026 发表杂志：Nature Communications

                            
                            Proteinase 3 Drives Murine Diabetic Kidney Disease by Mediating Caspase-3-dependent Apoptosis of Podocytes
                        

产品名称：Prtn3-Flox; Podocin-Cre

研究领域：糖尿病肾病; 细胞凋亡

发表年份：2026 发表杂志：KIDNEY INTERNATIONAL

                            
                            Microglial NCAM1 attenuates ischemic brain injury by inhibiting NF-κB-driven neuroinflammation through IκBα stabilization
                        

产品名称：Cx3cr1-CreERT2

研究领域：缺血性脑损伤; 小胶质细胞; 神经炎症

发表年份：2026 发表杂志：Journal of Neuroinflammation

                            
                            Targeting HSP90 destabilization with ganoderic acid a as a novel therapeutic strategy for hepatoblastoma
                        

产品名称：BALB/c

研究领域：肝母细胞瘤; 灵芝酸A; 靶向治疗

发表年份：2026 发表杂志：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

                            
                            Reactive astrocyte subpopulations with high Gfap and C4b expression in different Alzheimer’s disease mouse models: Single-cell nuclear transcriptome analysis
                        

产品名称：ApoE3-KI; ApoE4-KI; APP/PS1

研究领域：阿尔茨海默病; 反应性星形胶质细胞; 单细胞核转录组

发表年份：2026 发表杂志：Neural Regeneration Research

                            
                            Evolocumab alleviates atherogenesis by inhibiting inflammation-mediated endothelial cell activation via the PI3K/AKT/NF-κB pathway
                        

产品名称：ApoE-KO

研究领域：动脉粥样硬化; 内皮细胞活化; PI3K/AKT/NF-κB

发表年份：2026 发表杂志：EUROPEAN JOURNAL OF PHARMACOLOGY

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V2C MXene Nanozyme Attenuates Sepsis-Induced Gut Injury via Paneth Cell Death and ER Stress Regulation

Loss of p53 exacerbates autoimmunity by reprogramming propionyl-CoA metabolism and histone modifications in Treg cells

Renal Tubule-Specific Deletion of Nephrocystin 3 (Nphp3) Causes Infantile Nephronophthisis-like Phenotypes in Mice

Mrgprb4-Lineage Neurons Participate in the Intervention of TENS Effects on Chronic Pain and Anxiety-like Symptoms in an Inflammatory Pain Mouse Model

Pyruvate metabolism enzyme Dlat induces mitochondria protein hyperacetylation to limit fatty acid oxidation in the HFpEF heart

Proteinase 3 Drives Murine Diabetic Kidney Disease by Mediating Caspase-3-dependent Apoptosis of Podocytes

Microglial NCAM1 attenuates ischemic brain injury by inhibiting NF-κB-driven neuroinflammation through IκBα stabilization

Targeting HSP90 destabilization with ganoderic acid a as a novel therapeutic strategy for hepatoblastoma

Reactive astrocyte subpopulations with high Gfap and C4b expression in different Alzheimer’s disease mouse models: Single-cell nuclear transcriptome analysis

Evolocumab alleviates atherogenesis by inhibiting inflammation-mediated endothelial cell activation via the PI3K/AKT/NF-κB pathway

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