历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Organ-specific delivery of an mRNA-encoded bispecific T cell engager targeting glypican-3 in hepatocellular carcinoma
                        

产品名称：hCD3EDG

研究领域：TCE;肝癌;mRNA疗法;肿瘤

发表年份：2025 发表杂志：Nature Communications

                            
                            Slc22a17 governs postnatal neurogenesis by maintaining the iron homeostasis in hippocampus
                        

产品名称：slc22a17-flox

研究领域：神经;代谢;铁稳态;海马体

发表年份：2025 发表杂志：Nature Communications

Sex-dependent impact of Il6 deficiency in Parkinson's disease mice

产品名称：Il6-ko

研究领域：帕金森病;神经炎症

发表年份：2025 发表杂志：Genes & Diseases

                            
                            BRAP Promotes the Tumorigenesis of Hepatocellular Carcinoma by Corrupting Cancer Cell Cycle Regulation and Enhancing Immune Evasion
                        

产品名称：BALB/c Nude

研究领域：免疫逃逸;肝癌

发表年份：2025 发表杂志：Journal of Hepatocellular Carcinoma

                            
                            Fibrates Inhibit PLTP-induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs
                        

产品名称：H11-CAG-LSL-Myc;Alb-Cre-Tg

研究领域：肝癌;肿瘤;肿瘤免疫;M2巨噬细胞

发表年份：2025 发表杂志：Advanced Science

                            
                            A novel long-galanin peptide from non-mammalian vertebrates mitigates the inflammatory response in IBD models via the biased GALR2/β-arrestin2 pathway
                        

产品名称：Arrb2-flox

研究领域：炎症性肠炎;炎症

发表年份：2025 发表杂志：Nature Communications

                            
                            Dairy-rich diet triggers hepatic α-synuclein pathology via the liver-brain axis in GBA1-related Parkinson’s disease
                        

产品名称：Gba1-L444P

研究领域：帕金森病;神经

发表年份：2025 发表杂志：npj Parkinsons Disease

                            
                            The Artemisia argyi oil reduces high-fat diet-induced obesity by enhancing thermogenesis in brown adipose tissue
                        

产品名称：C57BL/6

研究领域：代谢;棕色脂肪组织

发表年份：2025 发表杂志：npj Science of Food

                            
                            MDM2-P53-V-ATPases axis driven by dehydroevodiamine to fight intracellular bacterial infection
                        

产品名称：Trp53-KO;Atp6v1f-KO

研究领域：抗菌耐药性;感染

发表年份：2025 发表杂志：Communications Biology

                            
                            Macrophage DHX34 as a negative regulator of the CX3CL1–CX3CR1 axis and CD8+ T-cell infiltration in hepatocellular carcinoma
                        

产品名称：Dhx34-Flox

研究领域：肿瘤相关巨噬细胞;肝细胞癌

发表年份：2025 发表杂志：INTERNATIONAL IMMUNOPHARMACOLOGY

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Organ-specific delivery of an mRNA-encoded bispecific T cell engager targeting glypican-3 in hepatocellular carcinoma

Slc22a17 governs postnatal neurogenesis by maintaining the iron homeostasis in hippocampus

Sex-dependent impact of Il6 deficiency in Parkinson's disease mice

BRAP Promotes the Tumorigenesis of Hepatocellular Carcinoma by Corrupting Cancer Cell Cycle Regulation and Enhancing Immune Evasion

Fibrates Inhibit PLTP-induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

A novel long-galanin peptide from non-mammalian vertebrates mitigates the inflammatory response in IBD models via the biased GALR2/β-arrestin2 pathway

Dairy-rich diet triggers hepatic α-synuclein pathology via the liver-brain axis in GBA1-related Parkinson’s disease

The Artemisia argyi oil reduces high-fat diet-induced obesity by enhancing thermogenesis in brown adipose tissue

MDM2-P53-V-ATPases axis driven by dehydroevodiamine to fight intracellular bacterial infection

Macrophage DHX34 as a negative regulator of the CX3CL1–CX3CR1 axis and CD8+ T-cell infiltration in hepatocellular carcinoma

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