hLRRC15

利用同源重组，将小鼠Lrrc15 基因进行人源化修饰。

Fig.1 Detection of LRRC15 expression in heart by RT-PCR. 

Wild type: only one band at 340 bp with primers F1/R1(mLrrc15);

Heterozygous: one band at 340 bp with primers F1/R1(mLrrc15) and one band at 207 bp with primers F2/R2(hLRRC15). 

Abbr. M, DNA marker; HE, heterozygous; WT, wild type.

Fig.2 Detection of human LRRC15 expression in hLRRC15 mice by WB. 

Abbr. M,marker; WT, wild type; HE,heterozygote.

Note. The anti-human LRRC15 Antibody cross-reacted with mouse LRRC15 and humanized LRRC15.