Cyp4v3-KO
品系全名
C57BL/6Smoc-Cyp4v3em1Smoc
目录号
NM-KO-200711
品系状态
活体
基因信息
基因名
Cyp4v3
品系描述
敲除Cyp4v3基因exon 2-6，建立Cyp4v3基因敲除小鼠模型。
*使用本品系发表的文献需注明: Cyp4v3-KO mice (Cat. NO. NM-KO-200711) were purchased from Shanghai Model Organisms Center, Inc..
疾病预测
Bietti结晶性角膜视网膜营养不良
Bietti Crystalline Corneoretinal Dystrophy
Bietti Crystalline Corneoretinal Dystrophy
验证数据
Fig.1 Detection of Cyp4v3 expression in the liver by qPCR.
Total RNA was extracted from wild-type C57BL/6J mice (WT) and homozygous Cyp4v3-KO mice (HO), which have been put on a high fat-diet for 49-50 weeks (male, 53-54 weeks old), then cDNA libraries were synthesized by reverse transcription, followed by qPCR with mouse Cyp4v3 and Gapdh primers. Relative expression represents Cyp4v3 mRNA levels relative to its average expression in WT mice.
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