历年文献基因敲除小鼠_转基因小鼠定制

                            
                            GSDME promotes MASLD by regulating pyroptosis, Drp1 citrullination-dependent mitochondrial dynamic, and energy balance in intestine and liver
                        

产品名称：Gsdme-KO

研究领域：自身免疫及炎症;代谢功能障碍相关脂肪性肝炎

发表年份：2024 发表杂志：CELL DEATH AND DIFFERENTIATION

                            
                            Intestinal epithelial damage-derived mtDNA activates STING-IL12 axis in dendritic cells to promote colitis
                        

产品名称：Tmem173-Flox;Lyz2-CreERT2-IRES

研究领域：自身免疫及炎症;结肠炎

发表年份：2024 发表杂志：Theranostics

                            
                            TRIM65/NF2/YAP1 Signaling Coordinately Orchestrates Metabolic and Immune Advantages in Hepatocellular Carcinoma
                        

产品名称：Trim65-eCKO1

研究领域：肿瘤及肿瘤免疫;肝细胞癌

发表年份：2024 发表杂志：Advanced Science

                            
                            Effect of Bioactive Black Phosphorus Nanomaterials on Cancer-Associated Fibroblast Heterogeneity in Pancreatic Cancer
                        

产品名称：KPC;BALB/c nude

研究领域：肿瘤及肿瘤免疫;胰腺癌癌

发表年份：2024 发表杂志：ACS Nano

                            
                            Targeting the transmembrane cytokine co-receptor neuropilin-1 in distal tubules improves renal injury and fibrosis
                        

产品名称：Nrp1-Flox

研究领域：自身免疫及炎症;肾损伤和纤维化

发表年份：2024 发表杂志：Nature Communications

                            
                            Perturbation of METTL1-mediated tRNA N7- methylguanosine modification induces senescence and aging
                        

产品名称：R26-CreERT2

研究领域：其它;衰老

发表年份：2024 发表杂志：Nature Communications

                            
                            rs-TAC PDC, a peptide drug-conjugate, for targeted delivery of tacrolimus and sericin alleviates podocyte injury in diabetic nephropathy
                        

产品名称：Itgav-Flox

研究领域：

发表年份：2024 发表杂志：Nano Today

                            
                            ATP6V0A1-dependent cholesterol absorption in colorectal cancer cells triggers immunosuppressive signaling to inactivate memory CD8+ T cells
                        

产品名称：Rag2/IL2rg-KO(BALB/c);Rag2/Il2rg-KO

研究领域：肿瘤及肿瘤免疫;结直肠癌

发表年份：2024 发表杂志：Nature Communications

                            
                            Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors
                        

产品名称：hCCR8(2)

研究领域：肿瘤及肿瘤免疫;卵巢癌

发表年份：2024 发表杂志：CELL

                            
                            ABCG2 shields against epilepsy, relieves oxidative stress and apoptosis via inhibiting the ISGylation of STAT1 and mTOR
                        

产品名称：Abcg2-KO

研究领域：神经;癫痫

发表年份：2024 发表杂志：Redox Biology

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GSDME promotes MASLD by regulating pyroptosis, Drp1 citrullination-dependent mitochondrial dynamic, and energy balance in intestine and liver

Intestinal epithelial damage-derived mtDNA activates STING-IL12 axis in dendritic cells to promote colitis

TRIM65/NF2/YAP1 Signaling Coordinately Orchestrates Metabolic and Immune Advantages in Hepatocellular Carcinoma

Effect of Bioactive Black Phosphorus Nanomaterials on Cancer-Associated Fibroblast Heterogeneity in Pancreatic Cancer

Targeting the transmembrane cytokine co-receptor neuropilin-1 in distal tubules improves renal injury and fibrosis

Perturbation of METTL1-mediated tRNA N7- methylguanosine modification induces senescence and aging

rs-TAC PDC, a peptide drug-conjugate, for targeted delivery of tacrolimus and sericin alleviates podocyte injury in diabetic nephropathy

ATP6V0A1-dependent cholesterol absorption in colorectal cancer cells triggers immunosuppressive signaling to inactivate memory CD8+ T cells

Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors

ABCG2 shields against epilepsy, relieves oxidative stress and apoptosis via inhibiting the ISGylation of STAT1 and mTOR

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