历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Targeting RBM39 through indisulam induced mis-splicing of mRNA to exert anti-cancer effects in T-cell acute lymphoblastic leukemia
                        

产品名称：M-NSG

研究领域：肿瘤及肿瘤免疫;T 细胞急性淋巴细胞白血病

发表年份：2024 发表杂志：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

                            
                            Trafficking circuit of CD8+ T cells between the intestine and bone marrow governs antitumour immunity
                        

产品名称：Cd8a-IRES-DTRGFP;Rag1-KO

研究领域：肿瘤及肿瘤免疫;白血病

发表年份：2024 发表杂志：NATURE CELL BIOLOGY

                            
                            Ca2+ transients on the T cell surface trigger rapid integrin activation in a timescale of seconds
                        

产品名称：Itgal-LSL-cc-mClover;Itgb2-LSL-mRuby2;R26-CAG-LSL-GEM-CEPIA1er

研究领域：自身免疫及炎症;整合素激活

发表年份：2024 发表杂志：Nature Communications

                            
                            Ketamine ameliorates post-traumatic social avoidance by erasing the traumatic memory encoded in VTA-innervated BLA engram cells
                        

产品名称：Slc6a3-IRES-Cre

研究领域：神经;创伤后应激障碍

发表年份：2024 发表杂志：NEURON

                            
                            Beta2 adrenergic receptor–mediated abnormal myelopoiesis drives neuroinflammation in aged patients with traumatic brain injury
                        

产品名称：Adrb2-KO;CAG-GFP-Tg

研究领域：神经;老年创伤性脑损伤

发表年份：2024 发表杂志：Science Advances

                            
                            Necroptosis enhances ‘don’t eat me’ signal and induces macrophage extracellular traps to promote pancreatic cancer liver metastasis
                        

产品名称：KPC;NOD SCID

研究领域：肿瘤及肿瘤免疫;胰腺导管腺癌

发表年份：2024 发表杂志：Nature Communications

                            
                            TWIST1+FAP+ fibroblasts in the pathogenesis of intestinal fibrosis in Crohn’s disease
                        

产品名称：Twist1-flox

研究领域：自身免疫及炎症;克罗恩病肠纤维化

发表年份：2024 发表杂志：JOURNAL OF CLINICAL INVESTIGATION

                            
                            CRIg+ macrophages deficiency enhanced inflammation damage in IBD due to gut extracellular vesicles containing microbial DNA
                        

产品名称：Vsig4-KO

研究领域：自身免疫及炎症;细胞外囊泡

发表年份：2024 发表杂志：Gut Microbes

                            
                            RNF213 promotes Treg cell differentiation by facilitating K63-linked ubiquitination and nuclear translocation of FOXO1
                        

产品名称：Rag1-KO(Rag1-EGFP);Cd45.1

研究领域：自身免疫及炎症;Treg 细胞分化

发表年份：2024 发表杂志：Nature Communications

                            
                            Antibody Fc-receptor FcεR1γ stabilizes cell surface receptors in group 3 innate lymphoid cells and promotes anti-infection immunity
                        

产品名称：Fcer1g-KO

研究领域：自身免疫及炎症;感染

发表年份：2024 发表杂志：Nature Communications

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Targeting RBM39 through indisulam induced mis-splicing of mRNA to exert anti-cancer effects in T-cell acute lymphoblastic leukemia

Trafficking circuit of CD8+ T cells between the intestine and bone marrow governs antitumour immunity

Ca2+ transients on the T cell surface trigger rapid integrin activation in a timescale of seconds

Ketamine ameliorates post-traumatic social avoidance by erasing the traumatic memory encoded in VTA-innervated BLA engram cells

Beta2 adrenergic receptor–mediated abnormal myelopoiesis drives neuroinflammation in aged patients with traumatic brain injury

Necroptosis enhances ‘don’t eat me’ signal and induces macrophage extracellular traps to promote pancreatic cancer liver metastasis

TWIST1+FAP+ fibroblasts in the pathogenesis of intestinal fibrosis in Crohn’s disease

CRIg+ macrophages deficiency enhanced inflammation damage in IBD due to gut extracellular vesicles containing microbial DNA

RNF213 promotes Treg cell differentiation by facilitating K63-linked ubiquitination and nuclear translocation of FOXO1

Antibody Fc-receptor FcεR1γ stabilizes cell surface receptors in group 3 innate lymphoid cells and promotes anti-infection immunity

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