历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Loss of hepatic ME1 ameliorates MASLD by Suppressing peroxisomal β-Oxidation and Activating Lipophagy/Lipolysis
                        

产品名称：Alb-CreERT2

研究领域：脂肪性肝病

发表年份：2025 发表杂志：Journal of Advanced Research

                            
                            CETN3 deficiency induces microcephaly by disrupting neural stem/progenitor cell fate through impaired centrosome assembly and RNA splicing
                        

产品名称：Emx1-IRES-Cre

研究领域：罕见病

发表年份：2025 发表杂志：EMBO Molecular Medicine

                            
                            Gut-derived indole propionic acid alleviates liver fibrosis by targeting profibrogenic macrophages via the gut‒liver axis
                        

产品名称：Ccr2-KO; Ahr-Flox; Lrat-2A-Cre

研究领域：自身免疫及炎症

发表年份：2025 发表杂志：Cellular & Molecular Immunology

                            
                            NR1I3 inhibits colorectal cancer growth by enhancing PCK1-mediated gluconeogenesis
                        

产品名称：BALB/c Nude

研究领域：肿瘤

发表年份：2025 发表杂志：CHEMICO-BIOLOGICAL INTERACTIONS

                            
                            Aurora kinase A promotes trained immunity via regulation of endogenous S-adenosylmethionine metabolism
                        

产品名称：Cd45.1

研究领域：肿瘤及肿瘤免疫

发表年份：2025 发表杂志：eLife

                            
                            RNF180 suppressed aggressiveness by degrading NOTCH1, TRIM24 and FOXC1, and chemoresistance by degrading ACC1 and ACLY in colorectal cancer
                        

产品名称：RNF180-Flox

研究领域：肿瘤免疫

发表年份：2025 发表杂志：INTERNATIONAL IMMUNOPHARMACOLOGY

                            
                            Sweroside Inhibits Inflammation and Alleviates Endothelial Injury and Atherosclerosis in Mice
                        

产品名称：Apoe-KO

研究领域：心血管

发表年份：2025 发表杂志：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

NAMPT Is A Novel Inhibitor of Vascular Calcification in Chronic Kidney Disease

产品名称：Nampt-Flox

研究领域：代谢心血管

发表年份：2025 发表杂志：ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

                            
                            Activation of Myeloid Dendritic Cells by Up-Regulating RAGE/JAK/STAT Pathway Induced by Cigarette Smoke Exposure in Mice With Emphysema
                        

产品名称：Ager-Flox/Cd11c-cre

研究领域：肺病免疫学

发表年份：2025 发表杂志：MEDIATORS OF INFLAMMATION

                            
                            AMPK maintains the activation of hepatic stellate cells through mitophagy-induced metabolic reprogramming
                        

产品名称：Lrat-2A-Cre

研究领域：线粒体

发表年份：2025 发表杂志：Journal of Molecular Cell Biology

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Loss of hepatic ME1 ameliorates MASLD by Suppressing peroxisomal β-Oxidation and Activating Lipophagy/Lipolysis

CETN3 deficiency induces microcephaly by disrupting neural stem/progenitor cell fate through impaired centrosome assembly and RNA splicing

Gut-derived indole propionic acid alleviates liver fibrosis by targeting profibrogenic macrophages via the gut‒liver axis

NR1I3 inhibits colorectal cancer growth by enhancing PCK1-mediated gluconeogenesis

Aurora kinase A promotes trained immunity via regulation of endogenous S-adenosylmethionine metabolism

RNF180 suppressed aggressiveness by degrading NOTCH1, TRIM24 and FOXC1, and chemoresistance by degrading ACC1 and ACLY in colorectal cancer

Sweroside Inhibits Inflammation and Alleviates Endothelial Injury and Atherosclerosis in Mice

NAMPT Is A Novel Inhibitor of Vascular Calcification in Chronic Kidney Disease

Activation of Myeloid Dendritic Cells by Up-Regulating RAGE/JAK/STAT Pathway Induced by Cigarette Smoke Exposure in Mice With Emphysema

AMPK maintains the activation of hepatic stellate cells through mitophagy-induced metabolic reprogramming

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