历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Glycyrrhiza polysaccharide-adjuvanted liposomal vaccine potentiates tumor immunotherapy through lymph node-targeted modulation of the DC-T cell axis
                        

产品名称：C57BL/6

研究领域：肿瘤免疫; 肿瘤疫苗

发表年份：2025 发表杂志：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

                            
                            Low SVEP1 in intrahepatic cholangiocarcinoma mediates phenotype switching-driven metastasis by Jag2/Notch1/Hes5
                        

产品名称：M-NSG

研究领域：肝内胆管癌; 肿瘤转移

发表年份：2025 发表杂志：Cell Death & Disease

                            
                            METTL3-mediated m6A modification of TIFA mRNA promotes tubular cell pyroptosis in acute kidney injury
                        

产品名称：METTL3-Flox

研究领域：急性肾损伤; m6A

发表年份：2025 发表杂志：FREE RADICAL BIOLOGY AND MEDICINE

                            
                            Preclinical Development and a Case Report of a Nanobody-Based CLDN18.2 CAR-T IMC002 with Reduced On-Target Off-Tumor Toxicity
                        

产品名称：M-NSG

研究领域：胃癌和胰腺癌; CLDN18.2 CAR-T

发表年份：2025 发表杂志：MOLECULAR CANCER THERAPEUTICS

                            
                            Type III Interferons attenuates Th1/Th17 cell pathogenicity and regulates retinal pigment epithelium cells via NLRP1/NLRP3 signaling axis in autoimmune uveitis
                        

产品名称：IFNLR1-KO

研究领域：自身免疫性疾病; 葡萄膜炎

发表年份：2025 发表杂志：Genes & Diseases

                            
                            Transcriptional deregulation by FOXM1–JUP signaling confers dual oncogenic drivers for pancreatic tumorigenesis and therapeutic resistance
                        

产品名称：KC;KPC

研究领域：胰腺导管腺癌

发表年份：2025 发表杂志：Cell Communication and Signaling

                            
                            Osteocytic FSH inhibition rescues bone mass and boosts fracture healing in ovariectomized mice
                        

产品名称：Fshr-Flox

研究领域：骨质疏松症; 骨形成

发表年份：2025 发表杂志：LIFE SCIENCES

Biased histamine signaling selectively gates fat preference

产品名称：Hrh3-Flox;Hrh1-Flox;HDC-CreERT2

研究领域：代谢;神经通路；脑-肠轴

发表年份：2025 发表杂志：NEURON

                            
                            MHC-II-restricted neoantigen vaccine reverses immune microenvironment and overcomes resistance to immune-checkpoint inhibitors in cold tumors
                        

产品名称：OT-II

研究领域：肿瘤免疫; 肿瘤微环境

发表年份：2025 发表杂志：Med

Extracellular vesicles for delivery of functional telomerase

产品名称：C57BL/6

研究领域：衰老; 端粒酶

发表年份：2025 发表杂志：Cell Communication and Signaling

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Glycyrrhiza polysaccharide-adjuvanted liposomal vaccine potentiates tumor immunotherapy through lymph node-targeted modulation of the DC-T cell axis

Low SVEP1 in intrahepatic cholangiocarcinoma mediates phenotype switching-driven metastasis by Jag2/Notch1/Hes5

METTL3-mediated m6A modification of TIFA mRNA promotes tubular cell pyroptosis in acute kidney injury

Preclinical Development and a Case Report of a Nanobody-Based CLDN18.2 CAR-T IMC002 with Reduced On-Target Off-Tumor Toxicity

Type III Interferons attenuates Th1/Th17 cell pathogenicity and regulates retinal pigment epithelium cells via NLRP1/NLRP3 signaling axis in autoimmune uveitis

Transcriptional deregulation by FOXM1–JUP signaling confers dual oncogenic drivers for pancreatic tumorigenesis and therapeutic resistance

Osteocytic FSH inhibition rescues bone mass and boosts fracture healing in ovariectomized mice

Biased histamine signaling selectively gates fat preference

MHC-II-restricted neoantigen vaccine reverses immune microenvironment and overcomes resistance to immune-checkpoint inhibitors in cold tumors

Extracellular vesicles for delivery of functional telomerase

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