历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Gut microbiota preserves bone mass through modulating the hyodeoxycholic acid–TGR5 axis
                        

产品名称：Gpbar1-KO

研究领域：骨质疏松;肠道微生物群;代谢

发表年份：2025 发表杂志：Gut Microbes

                            
                            Formononetin inhibits colorectal cancer via the miR-490-3p/ABCC2 axis and synergizes with 5-fluorouracil: mechanistic insights and therapeutic implications
                        

产品名称：Abcc2-KO

研究领域：结直肠癌;肿瘤

发表年份：2025 发表杂志：BIOCHEMICAL PHARMACOLOGY

                            
                            Therapeutic efficacy of Sanhuang Xiexin decoction on atopic dermatitis via suppressing STAT3 signaling
                        

产品名称：C57BL/6

研究领域：特应性皮炎

发表年份：2025 发表杂志：JOURNAL OF ETHNOPHARMACOLOGY

                            
                            Sex-dimorphic reprogramming of fetal mouse brain development by maternal estradiol excess
                        

产品名称：C57BL/6

研究领域：性别分化

发表年份：2025 发表杂志：Biology of Sex Differences

                            
                            4-Phenylbutyrate rescues neurobehavioral phenotypes in SLC6A1-related encephalopathy
                        

产品名称：Slc6a1-S295L

研究领域：癫痫;认知障碍

发表年份：2025 发表杂志：EPILEPSY RESEARCH

RNF10 is atherosclerosis protective and modulates macrophage polarization

产品名称：Rnf10-Flox;Lyz2-Cre

研究领域：动脉粥样硬化;炎症;巨噬细胞极化

发表年份：2025 发表杂志：EXPERIMENTAL ANIMALS

                            
                            Active-targeting biomimetic nanosystem for prostate cancer enhances radiotherapy efficacy by inducing ferroptosis
                        

产品名称：TRAMP

研究领域：前列腺癌; 放疗耐药性和非靶向毒性

发表年份：2025 发表杂志：JOURNAL OF NANOBIOTECHNOLOGY

                            
                            cGAS-STING signaling in the tumor microenvironment induces myeloid cell activation and favors T cell-mediated antitumor immunity
                        

产品名称：KPC

研究领域：肿瘤微环境; 肿瘤免疫

发表年份：2025 发表杂志：CANCER BIOLOGY & THERAPY

                            
                            Xuebijing injection alleviates sepsis-induced acute lung injury by triggering ferroptosis of CCR2hi monocytes
                        

产品名称：Ccr2-KO;Nrf2-KO

研究领域：败血症; 急性肺损伤

发表年份：2025 发表杂志：PHYTOMEDICINE

                            
                            Helicobacter pylori Lipopolysaccharide Upregulates MDM2 via the TLR4/MAPK/AP-1 Pathway to Promote Gastric Cancer Progression
                        

产品名称：C57BL/6

研究领域：胃癌; 幽门螺旋杆菌

发表年份：2025 发表杂志：DIGESTIVE DISEASES AND SCIENCES

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Gut microbiota preserves bone mass through modulating the hyodeoxycholic acid–TGR5 axis

Formononetin inhibits colorectal cancer via the miR-490-3p/ABCC2 axis and synergizes with 5-fluorouracil: mechanistic insights and therapeutic implications

Therapeutic efficacy of Sanhuang Xiexin decoction on atopic dermatitis via suppressing STAT3 signaling

Sex-dimorphic reprogramming of fetal mouse brain development by maternal estradiol excess

4-Phenylbutyrate rescues neurobehavioral phenotypes in SLC6A1-related encephalopathy

RNF10 is atherosclerosis protective and modulates macrophage polarization

Active-targeting biomimetic nanosystem for prostate cancer enhances radiotherapy efficacy by inducing ferroptosis

cGAS-STING signaling in the tumor microenvironment induces myeloid cell activation and favors T cell-mediated antitumor immunity

Xuebijing injection alleviates sepsis-induced acute lung injury by triggering ferroptosis of CCR2hi monocytes

Helicobacter pylori Lipopolysaccharide Upregulates MDM2 via the TLR4/MAPK/AP-1 Pathway to Promote Gastric Cancer Progression

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