多癌种全覆盖!总有一款原位移植瘤模型适合你!




异种移植小鼠模型,包括皮下异种移植(subcutaneous xenograft,SX)和原位异种移植(orthotopic xenograft,OX)模型,广泛用于研究肿瘤发生、抗癌药物的开发以及肿瘤关键分子机制的探索。


然而,越来越多的研究者认为,皮下移植瘤模型不能真正反馈肿瘤发生发展,且该模型对药物反应性差、转移发生率较低、生存曲线数据与临床脱节。并且,目前肿瘤免疫疗法兴起,针对肿瘤微环境的深入解析也成为提高免疫治疗效果的关键,皮下移植瘤模型已经不能满足肿瘤药物的研发需求,小鼠原位移植瘤模型成为大家更青睐的选择。


南模生物打造了全面专业的抗肿瘤药效评价平台,在构建小鼠原位移植瘤模型方面具有丰富的经验,目前已成功建立数十种小鼠原位肿瘤模型,可更好地满足不同癌种药物药效评价的需求。



若您有相关需求,欢迎拨打400-728-0660热线或于微信公众号在线咨询,我们的专业团队将竭诚为您服务!



关于我们


上海南方模式生物科技股份有限公司(Shanghai Model Organisms Center, Inc.,简称"南模生物"),成立于2000年9月,是一家上交所科创板上市高科技生物公司(股票代码:688265),始终以编辑基因、解码生命为己任,专注于模式生物领域,打造了以基因修饰动物模型研发为核心,涵盖多物种模型构建、饲养繁育、表型分析、药物临床前评价等多个技术平台,致力于为全球高校、科研院所、制药企业等客户提供全方位、一体化的基因修饰动物模型产品解决方案。





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