hMAPT-P301S
品系全名
C57BL/6JSmo-Mapttm1(hMAPT-P301S)Smoc
目录号
NM-KI-233262
品系状态
活体
基因信息
基因名
Mapt
品系描述
验证数据
Fig.1 Detection of hMAPT-P301S expression in brain by RT-PCR. (male, 7wks)
Wild type: only one band at 245 bp with primers F1/R1 (mMapt);
Heterozygous: one band at 245 bp with primers F1/R1 (hMAPT).
Abbr. M, DNA marker; HE, heterozygous; WT, wild type.
Fig.2 Sequencing results of the MAPT locus in the wild type and heterozygous hMAPT-P301S mice.
Fig.3 Detection of Phospho-Tau expression in brain in hMAPT-P301S mice by WB. (female, 24wks)
The relative gray values to GAPDH were quantitated by densitometry using ImageJ software.
Abbr. M, marker; WT, wild type; HO, homozygous.
Note. UnPaired t-test, *P < 0.01.
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