Lyz2-IRES-DTRGFP

品系全名

C57BL/6Smoc-Lyz2em3(IRES-DTREGFP)Smoc

目录号

NM-KI-190041

品系状态

活体

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基因信息

基因名
Lyz2

基因曾用名

Lys; Lzm; Lzp; Lysm; Lyzs; Lyzf2; Lzm-s1; AI326280

NCBI ID

17105

MGI ID

96897

Ensembl ID

ENSMUSG00000069516

Pubmed

Lyz2

人类同源基因

LYZ2

品系描述

A IRES-DTREGFP expression cassette was knocked into the Lyz2 gene stop codon site.
应用领域：DTR mouse

验证数据

1.png

Fig1. Analysis of GFP expression by FACS . The Lyz2-DTRGFP mouse expresses GFP on CD11b+ cells.


2.png

Fig2. Analysis of the level of different immune cells in PBMC by FACS (See Figure 4 for details of diphtheria toxin injection). 


3.png

Fig3. Analysis of the level of different immune cells in the spleen and transplanted tumor by FACS (See Figure 4 for details of diphtheria toxin injection). 

4.png

Fig4. The growth of MC38 tumors in Lyz2-DTRGFP mice and C57BL/6 mice. 

Heterozygous Lyz2-DTRGFP mice and C57BL/6 mice were inoculated with MC38 colon cancer cells.  The Lyz2-DTRGFP mice were injected with diphtheria toxin twice a week.

 The data is provided by Crownbio.

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