hF2RL1

品系全名

C57BL/6Smoc-F2rl1tm1(hF2RL1)Smoc

目录号

NM-HU-241165

品系状态

活体

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基因信息

基因名
F2rl1

品系描述

利用同源重组,将小鼠F2rl1基因进行人源化修饰。

验证数据

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Fig.1 Detection of F2RL1 expression in pancreas, stomach, ileum, large intestine and duodenum by RT-PCR. 

Wild type: only one band at 169 bp with primers F1/R1(mF2rl1);

Homozygous: only one band at 162 bp with primers F2/R2(hF2RL1).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hF2RL1 (A) and mF2RL1 (B) expression in pancreas, stomach, ileum, large intestine and duodenum by qPCR. (female, 8 weeks old)

(A) Relative expression represents the hF2RL1 mRNA levels relative to its average expression in the stomach of hF2RL1 knockin mice. 

(B) Relative expression represents the mF2rl1 mRNA levels relative to its average expression in the stomach of WT mice. 

Abbr. HO, homozygous; WT, wild type.

image.png

Fig.3 Detection of human F2RL1 expression in hF2RL1 knockin mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous; PC, positive control, HepG2 cells.


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